Müller glial microRNAs are required for the maintenance of glial homeostasis and retinal architecture

Müller glia are a type of retinal glial cell important for maintaining retinal structure and implicated in response to retinal damage. Here the authors identify Brevican, a chondroitin sulfate proteoglycan, as a microRNA-modulated regulator of Müller glia function.

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Detalles Bibliográficos
Autores principales: Stefanie G. Wohl, Nikolas L. Jorstad, Edward M. Levine, Thomas A. Reh
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/2934f8e7eaba4145a803c3a158948070
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Descripción
Sumario:Müller glia are a type of retinal glial cell important for maintaining retinal structure and implicated in response to retinal damage. Here the authors identify Brevican, a chondroitin sulfate proteoglycan, as a microRNA-modulated regulator of Müller glia function.