Müller glial microRNAs are required for the maintenance of glial homeostasis and retinal architecture

Müller glia are a type of retinal glial cell important for maintaining retinal structure and implicated in response to retinal damage. Here the authors identify Brevican, a chondroitin sulfate proteoglycan, as a microRNA-modulated regulator of Müller glia function.

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Autores principales: Stefanie G. Wohl, Nikolas L. Jorstad, Edward M. Levine, Thomas A. Reh
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/2934f8e7eaba4145a803c3a158948070
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spelling oai:doaj.org-article:2934f8e7eaba4145a803c3a1589480702021-12-02T15:38:59ZMüller glial microRNAs are required for the maintenance of glial homeostasis and retinal architecture10.1038/s41467-017-01624-y2041-1723https://doaj.org/article/2934f8e7eaba4145a803c3a1589480702017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01624-yhttps://doaj.org/toc/2041-1723Müller glia are a type of retinal glial cell important for maintaining retinal structure and implicated in response to retinal damage. Here the authors identify Brevican, a chondroitin sulfate proteoglycan, as a microRNA-modulated regulator of Müller glia function.Stefanie G. WohlNikolas L. JorstadEdward M. LevineThomas A. RehNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Stefanie G. Wohl
Nikolas L. Jorstad
Edward M. Levine
Thomas A. Reh
Müller glial microRNAs are required for the maintenance of glial homeostasis and retinal architecture
description Müller glia are a type of retinal glial cell important for maintaining retinal structure and implicated in response to retinal damage. Here the authors identify Brevican, a chondroitin sulfate proteoglycan, as a microRNA-modulated regulator of Müller glia function.
format article
author Stefanie G. Wohl
Nikolas L. Jorstad
Edward M. Levine
Thomas A. Reh
author_facet Stefanie G. Wohl
Nikolas L. Jorstad
Edward M. Levine
Thomas A. Reh
author_sort Stefanie G. Wohl
title Müller glial microRNAs are required for the maintenance of glial homeostasis and retinal architecture
title_short Müller glial microRNAs are required for the maintenance of glial homeostasis and retinal architecture
title_full Müller glial microRNAs are required for the maintenance of glial homeostasis and retinal architecture
title_fullStr Müller glial microRNAs are required for the maintenance of glial homeostasis and retinal architecture
title_full_unstemmed Müller glial microRNAs are required for the maintenance of glial homeostasis and retinal architecture
title_sort müller glial micrornas are required for the maintenance of glial homeostasis and retinal architecture
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/2934f8e7eaba4145a803c3a158948070
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AT nikolasljorstad mullerglialmicrornasarerequiredforthemaintenanceofglialhomeostasisandretinalarchitecture
AT edwardmlevine mullerglialmicrornasarerequiredforthemaintenanceofglialhomeostasisandretinalarchitecture
AT thomasareh mullerglialmicrornasarerequiredforthemaintenanceofglialhomeostasisandretinalarchitecture
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