GATA3 expression is decreased in psoriasis and during epidermal regeneration; induction by narrow-band UVB and IL-4.
Psoriasis is characterized by hyperproliferation of keratinocytes and by infiltration of activated Th1 and Th17 cells in the (epi)dermis. By expression microarray, we previously found the GATA3 transcription factor significantly downregulated in lesional psoriatic skin. Since GATA3 serves as a key s...
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Main Authors: | Emoke Rácz, Dorota Kurek, Marius Kant, Ewout M Baerveldt, Edwin Florencia, Sabine Mourits, Dick de Ridder, Jon D Laman, Leslie van der Fits, Errol P Prens |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2011
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Online Access: | https://doaj.org/article/29378433bed34f2687c5267b85d2c84f |
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