Emerging risk of Dirofilaria spp. infection in Northeastern Europe: high prevalence of Dirofilaria repens in sled dog kennels from the Baltic countries

Abstract Dirofilariasis is a fast-spreading disease of dogs and humans in Europe. We investigated whether Dirofilaria spp. have spread northwards in Europe, invading the Baltic countries. Altogether, 424 blood samples were collected from eight countries in the period 2017–2019, including 227 samples...

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Autores principales:	Mustafa Alsarraf, Viktoria Levytska, Ewa J. Mierzejewska, Vasyl Poliukhovych, Anna Rodo, Mohammed Alsarraf, Dziyana Kavalevich, Dorota Dwużnik-Szarek, Jerzy M. Behnke, Anna Bajer
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/2939d3386f604463bf1d85ca114bbf6c
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spelling	oai:doaj.org-article:2939d3386f604463bf1d85ca114bbf6c2021-12-02T15:23:09ZEmerging risk of Dirofilaria spp. infection in Northeastern Europe: high prevalence of Dirofilaria repens in sled dog kennels from the Baltic countries10.1038/s41598-020-80208-12045-2322https://doaj.org/article/2939d3386f604463bf1d85ca114bbf6c2021-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-80208-1https://doaj.org/toc/2045-2322Abstract Dirofilariasis is a fast-spreading disease of dogs and humans in Europe. We investigated whether Dirofilaria spp. have spread northwards in Europe, invading the Baltic countries. Altogether, 424 blood samples were collected from eight countries in the period 2017–2019, including 227 samples from sled dogs and 197 samples from other dogs. PCR amplification and sequencing were conducted employing three genetic markers (mitochondrial [mt] 12S rDNA, mt cytochrome c oxidase subunit I [COI] gene and mt dehydrogenase subunit I [NAD1] gene). The SNAP test (IDEXX) for detection of D. immitis infections was also implemented. The DNA of D. repens was detected in 59 of 424 dogs (prevalence 13.9%). D. repens was found in sled dogs from Lithuania, Latvia, Poland and Belarus. Only one dog from Estonia was infected, apparently an imported case. The highest prevalence was recorded in Lithuania (38%). Among pet dogs from the Ukraine, six dogs tested positive (3.8%). Our study has revealed a high prevalence of D. repens infections in Lithuania and Latvia, but no evidence for spread of the heartworm D. immitis. We conclude that sled dog kennels constitute hot spots for D. repens transmission.Mustafa AlsarrafViktoria LevytskaEwa J. MierzejewskaVasyl PoliukhovychAnna RodoMohammed AlsarrafDziyana KavalevichDorota Dwużnik-SzarekJerzy M. BehnkeAnna BajerNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Mustafa Alsarraf Viktoria Levytska Ewa J. Mierzejewska Vasyl Poliukhovych Anna Rodo Mohammed Alsarraf Dziyana Kavalevich Dorota Dwużnik-Szarek Jerzy M. Behnke Anna Bajer Emerging risk of Dirofilaria spp. infection in Northeastern Europe: high prevalence of Dirofilaria repens in sled dog kennels from the Baltic countries
description	Abstract Dirofilariasis is a fast-spreading disease of dogs and humans in Europe. We investigated whether Dirofilaria spp. have spread northwards in Europe, invading the Baltic countries. Altogether, 424 blood samples were collected from eight countries in the period 2017–2019, including 227 samples from sled dogs and 197 samples from other dogs. PCR amplification and sequencing were conducted employing three genetic markers (mitochondrial [mt] 12S rDNA, mt cytochrome c oxidase subunit I [COI] gene and mt dehydrogenase subunit I [NAD1] gene). The SNAP test (IDEXX) for detection of D. immitis infections was also implemented. The DNA of D. repens was detected in 59 of 424 dogs (prevalence 13.9%). D. repens was found in sled dogs from Lithuania, Latvia, Poland and Belarus. Only one dog from Estonia was infected, apparently an imported case. The highest prevalence was recorded in Lithuania (38%). Among pet dogs from the Ukraine, six dogs tested positive (3.8%). Our study has revealed a high prevalence of D. repens infections in Lithuania and Latvia, but no evidence for spread of the heartworm D. immitis. We conclude that sled dog kennels constitute hot spots for D. repens transmission.
format	article
author	Mustafa Alsarraf Viktoria Levytska Ewa J. Mierzejewska Vasyl Poliukhovych Anna Rodo Mohammed Alsarraf Dziyana Kavalevich Dorota Dwużnik-Szarek Jerzy M. Behnke Anna Bajer
author_facet	Mustafa Alsarraf Viktoria Levytska Ewa J. Mierzejewska Vasyl Poliukhovych Anna Rodo Mohammed Alsarraf Dziyana Kavalevich Dorota Dwużnik-Szarek Jerzy M. Behnke Anna Bajer
author_sort	Mustafa Alsarraf
title	Emerging risk of Dirofilaria spp. infection in Northeastern Europe: high prevalence of Dirofilaria repens in sled dog kennels from the Baltic countries
title_short	Emerging risk of Dirofilaria spp. infection in Northeastern Europe: high prevalence of Dirofilaria repens in sled dog kennels from the Baltic countries
title_full	Emerging risk of Dirofilaria spp. infection in Northeastern Europe: high prevalence of Dirofilaria repens in sled dog kennels from the Baltic countries
title_fullStr	Emerging risk of Dirofilaria spp. infection in Northeastern Europe: high prevalence of Dirofilaria repens in sled dog kennels from the Baltic countries
title_full_unstemmed	Emerging risk of Dirofilaria spp. infection in Northeastern Europe: high prevalence of Dirofilaria repens in sled dog kennels from the Baltic countries
title_sort	emerging risk of dirofilaria spp. infection in northeastern europe: high prevalence of dirofilaria repens in sled dog kennels from the baltic countries
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/2939d3386f604463bf1d85ca114bbf6c
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Emerging risk of Dirofilaria spp. infection in Northeastern Europe: high prevalence of Dirofilaria repens in sled dog kennels from the Baltic countries

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