Quantifying accuracy and heterogeneity in single-molecule super-resolution microscopy

Standard benchmarking of single-molecule localization microscopy cannot quantify nanoscale accuracy of arbitrary datasets. Here, the authors present Wasserstein-induced flux, a method using a chosen perturbation and knowledge of the imaging system to measure confidence of individual localizations.

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Autores principales:	Hesam Mazidi, Tianben Ding, Arye Nehorai, Matthew D. Lew
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/293de6b5849b489dbc388634cd7aeec1
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spelling	oai:doaj.org-article:293de6b5849b489dbc388634cd7aeec12021-12-02T13:23:47ZQuantifying accuracy and heterogeneity in single-molecule super-resolution microscopy10.1038/s41467-020-20056-92041-1723https://doaj.org/article/293de6b5849b489dbc388634cd7aeec12020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20056-9https://doaj.org/toc/2041-1723Standard benchmarking of single-molecule localization microscopy cannot quantify nanoscale accuracy of arbitrary datasets. Here, the authors present Wasserstein-induced flux, a method using a chosen perturbation and knowledge of the imaging system to measure confidence of individual localizations.Hesam MazidiTianben DingArye NehoraiMatthew D. LewNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hesam Mazidi Tianben Ding Arye Nehorai Matthew D. Lew Quantifying accuracy and heterogeneity in single-molecule super-resolution microscopy
description	Standard benchmarking of single-molecule localization microscopy cannot quantify nanoscale accuracy of arbitrary datasets. Here, the authors present Wasserstein-induced flux, a method using a chosen perturbation and knowledge of the imaging system to measure confidence of individual localizations.
format	article
author	Hesam Mazidi Tianben Ding Arye Nehorai Matthew D. Lew
author_facet	Hesam Mazidi Tianben Ding Arye Nehorai Matthew D. Lew
author_sort	Hesam Mazidi
title	Quantifying accuracy and heterogeneity in single-molecule super-resolution microscopy
title_short	Quantifying accuracy and heterogeneity in single-molecule super-resolution microscopy
title_full	Quantifying accuracy and heterogeneity in single-molecule super-resolution microscopy
title_fullStr	Quantifying accuracy and heterogeneity in single-molecule super-resolution microscopy
title_full_unstemmed	Quantifying accuracy and heterogeneity in single-molecule super-resolution microscopy
title_sort	quantifying accuracy and heterogeneity in single-molecule super-resolution microscopy
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/293de6b5849b489dbc388634cd7aeec1
work_keys_str_mv	AT hesammazidi quantifyingaccuracyandheterogeneityinsinglemoleculesuperresolutionmicroscopy AT tianbending quantifyingaccuracyandheterogeneityinsinglemoleculesuperresolutionmicroscopy AT aryenehorai quantifyingaccuracyandheterogeneityinsinglemoleculesuperresolutionmicroscopy AT matthewdlew quantifyingaccuracyandheterogeneityinsinglemoleculesuperresolutionmicroscopy
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Quantifying accuracy and heterogeneity in single-molecule super-resolution microscopy

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