Quantifying accuracy and heterogeneity in single-molecule super-resolution microscopy
Standard benchmarking of single-molecule localization microscopy cannot quantify nanoscale accuracy of arbitrary datasets. Here, the authors present Wasserstein-induced flux, a method using a chosen perturbation and knowledge of the imaging system to measure confidence of individual localizations.
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Main Authors: | Hesam Mazidi, Tianben Ding, Arye Nehorai, Matthew D. Lew |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2020
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Subjects: | |
Online Access: | https://doaj.org/article/293de6b5849b489dbc388634cd7aeec1 |
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