TRPM7 is an essential regulator for volume-sensitive outwardly rectifying anion channel
Numata et al examine whether the TRPM7 ion channel plays a role in the activation of volume-sensitive outwardly rectifying Cl− channels (VSOR) using human and chicken cell lines. By genetically-manipulating the expression of TRPM7 and performing electrophysiology, they demonstrate that TRPM7 is an e...
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2021
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oai:doaj.org-article:29513fd41dd64daea937648e873145ca2021-12-02T16:49:37ZTRPM7 is an essential regulator for volume-sensitive outwardly rectifying anion channel10.1038/s42003-021-02127-92399-3642https://doaj.org/article/29513fd41dd64daea937648e873145ca2021-05-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02127-9https://doaj.org/toc/2399-3642Numata et al examine whether the TRPM7 ion channel plays a role in the activation of volume-sensitive outwardly rectifying Cl− channels (VSOR) using human and chicken cell lines. By genetically-manipulating the expression of TRPM7 and performing electrophysiology, they demonstrate that TRPM7 is an essential regulator of VSOR activity.Tomohiro NumataKaori Sato-NumataMeredith C. HermosuraYasuo MoriYasunobu OkadaNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-14 (2021) |
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DOAJ |
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Biology (General) QH301-705.5 |
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Biology (General) QH301-705.5 Tomohiro Numata Kaori Sato-Numata Meredith C. Hermosura Yasuo Mori Yasunobu Okada TRPM7 is an essential regulator for volume-sensitive outwardly rectifying anion channel |
description |
Numata et al examine whether the TRPM7 ion channel plays a role in the activation of volume-sensitive outwardly rectifying Cl− channels (VSOR) using human and chicken cell lines. By genetically-manipulating the expression of TRPM7 and performing electrophysiology, they demonstrate that TRPM7 is an essential regulator of VSOR activity. |
format |
article |
author |
Tomohiro Numata Kaori Sato-Numata Meredith C. Hermosura Yasuo Mori Yasunobu Okada |
author_facet |
Tomohiro Numata Kaori Sato-Numata Meredith C. Hermosura Yasuo Mori Yasunobu Okada |
author_sort |
Tomohiro Numata |
title |
TRPM7 is an essential regulator for volume-sensitive outwardly rectifying anion channel |
title_short |
TRPM7 is an essential regulator for volume-sensitive outwardly rectifying anion channel |
title_full |
TRPM7 is an essential regulator for volume-sensitive outwardly rectifying anion channel |
title_fullStr |
TRPM7 is an essential regulator for volume-sensitive outwardly rectifying anion channel |
title_full_unstemmed |
TRPM7 is an essential regulator for volume-sensitive outwardly rectifying anion channel |
title_sort |
trpm7 is an essential regulator for volume-sensitive outwardly rectifying anion channel |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/29513fd41dd64daea937648e873145ca |
work_keys_str_mv |
AT tomohironumata trpm7isanessentialregulatorforvolumesensitiveoutwardlyrectifyinganionchannel AT kaorisatonumata trpm7isanessentialregulatorforvolumesensitiveoutwardlyrectifyinganionchannel AT meredithchermosura trpm7isanessentialregulatorforvolumesensitiveoutwardlyrectifyinganionchannel AT yasuomori trpm7isanessentialregulatorforvolumesensitiveoutwardlyrectifyinganionchannel AT yasunobuokada trpm7isanessentialregulatorforvolumesensitiveoutwardlyrectifyinganionchannel |
_version_ |
1718383266767044608 |