Rapid 16S rRNA next-generation sequencing of polymicrobial clinical samples for diagnosis of complex bacterial infections.

Classifying individual bacterial species comprising complex, polymicrobial patient specimens remains a challenge for culture-based and molecular microbiology techniques in common clinical use. We therefore adapted practices from metagenomics research to rapidly catalog the bacterial composition of c...

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Autores principales: Stephen J Salipante, Dhruba J Sengupta, Christopher Rosenthal, Gina Costa, Jessica Spangler, Elizabeth H Sims, Michael A Jacobs, Samuel I Miller, Daniel R Hoogestraat, Brad T Cookson, Connor McCoy, Frederick A Matsen, Jay Shendure, Clarence C Lee, Timothy T Harkins, Noah G Hoffman
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/295dd7c1af2b470e95163724ac3d7e51
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