CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks

Chromatin is dynamically remodeled in response to DNA damage in favour of repair. Here the authors reveal how the chromatin remodeler CHD7 and chromatin binding protein 53BP1 regulate distinct DNA repair pathways.

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Autores principales: Magdalena B. Rother, Stefania Pellegrino, Rebecca Smith, Marco Gatti, Cornelia Meisenberg, Wouter W. Wiegant, Martijn S. Luijsterburg, Ralph Imhof, Jessica A. Downs, Alfred C. O. Vertegaal, Sébastien Huet, Matthias Altmeyer, Haico van Attikum
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/297076b4803a47eba7a1ecb7f931f8c7
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spelling oai:doaj.org-article:297076b4803a47eba7a1ecb7f931f8c72021-12-02T14:40:39ZCHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks10.1038/s41467-020-19502-52041-1723https://doaj.org/article/297076b4803a47eba7a1ecb7f931f8c72020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19502-5https://doaj.org/toc/2041-1723Chromatin is dynamically remodeled in response to DNA damage in favour of repair. Here the authors reveal how the chromatin remodeler CHD7 and chromatin binding protein 53BP1 regulate distinct DNA repair pathways.Magdalena B. RotherStefania PellegrinoRebecca SmithMarco GattiCornelia MeisenbergWouter W. WiegantMartijn S. LuijsterburgRalph ImhofJessica A. DownsAlfred C. O. VertegaalSébastien HuetMatthias AltmeyerHaico van AttikumNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Magdalena B. Rother
Stefania Pellegrino
Rebecca Smith
Marco Gatti
Cornelia Meisenberg
Wouter W. Wiegant
Martijn S. Luijsterburg
Ralph Imhof
Jessica A. Downs
Alfred C. O. Vertegaal
Sébastien Huet
Matthias Altmeyer
Haico van Attikum
CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks
description Chromatin is dynamically remodeled in response to DNA damage in favour of repair. Here the authors reveal how the chromatin remodeler CHD7 and chromatin binding protein 53BP1 regulate distinct DNA repair pathways.
format article
author Magdalena B. Rother
Stefania Pellegrino
Rebecca Smith
Marco Gatti
Cornelia Meisenberg
Wouter W. Wiegant
Martijn S. Luijsterburg
Ralph Imhof
Jessica A. Downs
Alfred C. O. Vertegaal
Sébastien Huet
Matthias Altmeyer
Haico van Attikum
author_facet Magdalena B. Rother
Stefania Pellegrino
Rebecca Smith
Marco Gatti
Cornelia Meisenberg
Wouter W. Wiegant
Martijn S. Luijsterburg
Ralph Imhof
Jessica A. Downs
Alfred C. O. Vertegaal
Sébastien Huet
Matthias Altmeyer
Haico van Attikum
author_sort Magdalena B. Rother
title CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks
title_short CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks
title_full CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks
title_fullStr CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks
title_full_unstemmed CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks
title_sort chd7 and 53bp1 regulate distinct pathways for the re-ligation of dna double-strand breaks
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/297076b4803a47eba7a1ecb7f931f8c7
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