G-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis

Boleij et al. show that G protein-coupled receptor 35 (GPR35) regulates the responses to enterotoxigenic Bacteroides fragilis (ETBF) in colonic epithelial cells. They find that GPR35-deficiency nearly protected mice from ETBF-induced death, suggesting the importance of GPR35 in sensing ETBF in the c...

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Autores principales:	Annemarie Boleij, Payam Fathi, William Dalton, Ben Park, Xinqun Wu, David Huso, Jawara Allen, Sepideh Besharati, Robert A. Anders, Franck Housseau, Amanda E. Mackenzie, Laura Jenkins, Graeme. Milligan, Shaoguang Wu, Cynthia L. Sears
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/2986eba9551643dc8608d3a4c5b5b496
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spelling	oai:doaj.org-article:2986eba9551643dc8608d3a4c5b5b4962021-12-02T16:50:22ZG-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis10.1038/s42003-021-02014-32399-3642https://doaj.org/article/2986eba9551643dc8608d3a4c5b5b4962021-05-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02014-3https://doaj.org/toc/2399-3642Boleij et al. show that G protein-coupled receptor 35 (GPR35) regulates the responses to enterotoxigenic Bacteroides fragilis (ETBF) in colonic epithelial cells. They find that GPR35-deficiency nearly protected mice from ETBF-induced death, suggesting the importance of GPR35 in sensing ETBF in the colon.Annemarie BoleijPayam FathiWilliam DaltonBen ParkXinqun WuDavid HusoJawara AllenSepideh BesharatiRobert A. AndersFranck HousseauAmanda E. MackenzieLaura JenkinsGraeme. MilliganShaoguang WuCynthia L. SearsNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Annemarie Boleij Payam Fathi William Dalton Ben Park Xinqun Wu David Huso Jawara Allen Sepideh Besharati Robert A. Anders Franck Housseau Amanda E. Mackenzie Laura Jenkins Graeme. Milligan Shaoguang Wu Cynthia L. Sears G-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis
description	Boleij et al. show that G protein-coupled receptor 35 (GPR35) regulates the responses to enterotoxigenic Bacteroides fragilis (ETBF) in colonic epithelial cells. They find that GPR35-deficiency nearly protected mice from ETBF-induced death, suggesting the importance of GPR35 in sensing ETBF in the colon.
format	article
author	Annemarie Boleij Payam Fathi William Dalton Ben Park Xinqun Wu David Huso Jawara Allen Sepideh Besharati Robert A. Anders Franck Housseau Amanda E. Mackenzie Laura Jenkins Graeme. Milligan Shaoguang Wu Cynthia L. Sears
author_facet	Annemarie Boleij Payam Fathi William Dalton Ben Park Xinqun Wu David Huso Jawara Allen Sepideh Besharati Robert A. Anders Franck Housseau Amanda E. Mackenzie Laura Jenkins Graeme. Milligan Shaoguang Wu Cynthia L. Sears
author_sort	Annemarie Boleij
title	G-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis
title_short	G-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis
title_full	G-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis
title_fullStr	G-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis
title_full_unstemmed	G-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis
title_sort	g-protein coupled receptor 35 (gpr35) regulates the colonic epithelial cell response to enterotoxigenic bacteroides fragilis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/2986eba9551643dc8608d3a4c5b5b496
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G-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis

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