Genetic architecture of type 1 diabetes with low genetic risk score informed by 41 unreported loci

Hui-Qi Qu et al. present a case-control association study to examine the genetic architecture of European patients with type 1 diabetes (T1D) of low genetic risk score. They identify 41 loci associated with T1D of low genetic risk score, including regions previously linked to viral infection and aut...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Hui-Qi Qu, Jingchun Qu, Jonathan Bradfield, Luc Marchand, Joseph Glessner, Xiao Chang, Michael March, Jin Li, John J. Connolly, Jeffrey D. Roizen, Patrick Sleiman, Constantin Polychronakos, Hakon Hakonarson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/299624c58fdb434482bd26884aea79ed
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:299624c58fdb434482bd26884aea79ed
record_format	dspace
spelling	oai:doaj.org-article:299624c58fdb434482bd26884aea79ed2021-12-02T16:26:20ZGenetic architecture of type 1 diabetes with low genetic risk score informed by 41 unreported loci10.1038/s42003-021-02368-82399-3642https://doaj.org/article/299624c58fdb434482bd26884aea79ed2021-07-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02368-8https://doaj.org/toc/2399-3642Hui-Qi Qu et al. present a case-control association study to examine the genetic architecture of European patients with type 1 diabetes (T1D) of low genetic risk score. They identify 41 loci associated with T1D of low genetic risk score, including regions previously linked to viral infection and autism spectrum disorder, altogether providing further insight into the pathogenesis of T1D.Hui-Qi QuJingchun QuJonathan BradfieldLuc MarchandJoseph GlessnerXiao ChangMichael MarchJin LiJohn J. ConnollyJeffrey D. RoizenPatrick SleimanConstantin PolychronakosHakon HakonarsonNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Hui-Qi Qu Jingchun Qu Jonathan Bradfield Luc Marchand Joseph Glessner Xiao Chang Michael March Jin Li John J. Connolly Jeffrey D. Roizen Patrick Sleiman Constantin Polychronakos Hakon Hakonarson Genetic architecture of type 1 diabetes with low genetic risk score informed by 41 unreported loci
description	Hui-Qi Qu et al. present a case-control association study to examine the genetic architecture of European patients with type 1 diabetes (T1D) of low genetic risk score. They identify 41 loci associated with T1D of low genetic risk score, including regions previously linked to viral infection and autism spectrum disorder, altogether providing further insight into the pathogenesis of T1D.
format	article
author	Hui-Qi Qu Jingchun Qu Jonathan Bradfield Luc Marchand Joseph Glessner Xiao Chang Michael March Jin Li John J. Connolly Jeffrey D. Roizen Patrick Sleiman Constantin Polychronakos Hakon Hakonarson
author_facet	Hui-Qi Qu Jingchun Qu Jonathan Bradfield Luc Marchand Joseph Glessner Xiao Chang Michael March Jin Li John J. Connolly Jeffrey D. Roizen Patrick Sleiman Constantin Polychronakos Hakon Hakonarson
author_sort	Hui-Qi Qu
title	Genetic architecture of type 1 diabetes with low genetic risk score informed by 41 unreported loci
title_short	Genetic architecture of type 1 diabetes with low genetic risk score informed by 41 unreported loci
title_full	Genetic architecture of type 1 diabetes with low genetic risk score informed by 41 unreported loci
title_fullStr	Genetic architecture of type 1 diabetes with low genetic risk score informed by 41 unreported loci
title_full_unstemmed	Genetic architecture of type 1 diabetes with low genetic risk score informed by 41 unreported loci
title_sort	genetic architecture of type 1 diabetes with low genetic risk score informed by 41 unreported loci
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/299624c58fdb434482bd26884aea79ed
work_keys_str_mv	AT huiqiqu geneticarchitectureoftype1diabeteswithlowgeneticriskscoreinformedby41unreportedloci AT jingchunqu geneticarchitectureoftype1diabeteswithlowgeneticriskscoreinformedby41unreportedloci AT jonathanbradfield geneticarchitectureoftype1diabeteswithlowgeneticriskscoreinformedby41unreportedloci AT lucmarchand geneticarchitectureoftype1diabeteswithlowgeneticriskscoreinformedby41unreportedloci AT josephglessner geneticarchitectureoftype1diabeteswithlowgeneticriskscoreinformedby41unreportedloci AT xiaochang geneticarchitectureoftype1diabeteswithlowgeneticriskscoreinformedby41unreportedloci AT michaelmarch geneticarchitectureoftype1diabeteswithlowgeneticriskscoreinformedby41unreportedloci AT jinli geneticarchitectureoftype1diabeteswithlowgeneticriskscoreinformedby41unreportedloci AT johnjconnolly geneticarchitectureoftype1diabeteswithlowgeneticriskscoreinformedby41unreportedloci AT jeffreydroizen geneticarchitectureoftype1diabeteswithlowgeneticriskscoreinformedby41unreportedloci AT patricksleiman geneticarchitectureoftype1diabeteswithlowgeneticriskscoreinformedby41unreportedloci AT constantinpolychronakos geneticarchitectureoftype1diabeteswithlowgeneticriskscoreinformedby41unreportedloci AT hakonhakonarson geneticarchitectureoftype1diabeteswithlowgeneticriskscoreinformedby41unreportedloci
_version_	1718384040900296704

Genetic architecture of type 1 diabetes with low genetic risk score informed by 41 unreported loci

Ejemplares similares