Antioxidant Effects of Protocatechuic Acid and Protocatechuic Aldehyde: Old Wine in a New Bottle

Phenolic compounds are naturally present as secondary metabolites in plant-based sources such as fruits, vegetables, and spices. They have received considerable attention for their antioxidant, anti-inflammatory, and anti-carcinogenic properties for protection against many chronic disorders such as...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Shijun Zhang, Zhibo Gai, Ting Gui, Juanli Chen, Qingfa Chen, Yunlun Li
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Other systems of medicine RZ201-999
Acceso en línea:	https://doaj.org/article/29980526642c44fca7b8048f536a4d5e
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:29980526642c44fca7b8048f536a4d5e
record_format	dspace
spelling	oai:doaj.org-article:29980526642c44fca7b8048f536a4d5e2021-11-22T01:11:08ZAntioxidant Effects of Protocatechuic Acid and Protocatechuic Aldehyde: Old Wine in a New Bottle1741-428810.1155/2021/6139308https://doaj.org/article/29980526642c44fca7b8048f536a4d5e2021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/6139308https://doaj.org/toc/1741-4288Phenolic compounds are naturally present as secondary metabolites in plant-based sources such as fruits, vegetables, and spices. They have received considerable attention for their antioxidant, anti-inflammatory, and anti-carcinogenic properties for protection against many chronic disorders such as neurodegenerative diseases, diabetes, cardiovascular diseases, and cancer. They are categorized into various groups based on their chemical structure and include phenolic acids, flavonoids, curcumins, tannins, and quinolones. Their structural variations contribute to their specific beneficial effects on human health. The antioxidant property of phenolic compounds protects against oxidative stress by up-regulation of endogenous antioxidants, scavenging free radicals, and anti-apoptotic activity. Protocatechuic acid (PCA; 3,4-dihydroxy benzoic acid) and protocatechuic aldehyde (PAL; 3,4-dihydroxybenzaldehyde) are naturally occurring polyphenols found in vegetables, fruits, and herbs. PCA and PAL are the primary metabolites of anthocyanins and proanthocyanidins, which have been shown to possess pharmacological actions including antioxidant activity in vitro and in vivo. This review aims to explore the therapeutic potential of PCA and PAL by comprehensively summarizing their pharmacological properties reported to date, with an emphasis on their mechanisms of action and biological properties.Shijun ZhangZhibo GaiTing GuiJuanli ChenQingfa ChenYunlun LiHindawi LimitedarticleOther systems of medicineRZ201-999ENEvidence-Based Complementary and Alternative Medicine, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Other systems of medicine RZ201-999
spellingShingle	Other systems of medicine RZ201-999 Shijun Zhang Zhibo Gai Ting Gui Juanli Chen Qingfa Chen Yunlun Li Antioxidant Effects of Protocatechuic Acid and Protocatechuic Aldehyde: Old Wine in a New Bottle
description	Phenolic compounds are naturally present as secondary metabolites in plant-based sources such as fruits, vegetables, and spices. They have received considerable attention for their antioxidant, anti-inflammatory, and anti-carcinogenic properties for protection against many chronic disorders such as neurodegenerative diseases, diabetes, cardiovascular diseases, and cancer. They are categorized into various groups based on their chemical structure and include phenolic acids, flavonoids, curcumins, tannins, and quinolones. Their structural variations contribute to their specific beneficial effects on human health. The antioxidant property of phenolic compounds protects against oxidative stress by up-regulation of endogenous antioxidants, scavenging free radicals, and anti-apoptotic activity. Protocatechuic acid (PCA; 3,4-dihydroxy benzoic acid) and protocatechuic aldehyde (PAL; 3,4-dihydroxybenzaldehyde) are naturally occurring polyphenols found in vegetables, fruits, and herbs. PCA and PAL are the primary metabolites of anthocyanins and proanthocyanidins, which have been shown to possess pharmacological actions including antioxidant activity in vitro and in vivo. This review aims to explore the therapeutic potential of PCA and PAL by comprehensively summarizing their pharmacological properties reported to date, with an emphasis on their mechanisms of action and biological properties.
format	article
author	Shijun Zhang Zhibo Gai Ting Gui Juanli Chen Qingfa Chen Yunlun Li
author_facet	Shijun Zhang Zhibo Gai Ting Gui Juanli Chen Qingfa Chen Yunlun Li
author_sort	Shijun Zhang
title	Antioxidant Effects of Protocatechuic Acid and Protocatechuic Aldehyde: Old Wine in a New Bottle
title_short	Antioxidant Effects of Protocatechuic Acid and Protocatechuic Aldehyde: Old Wine in a New Bottle
title_full	Antioxidant Effects of Protocatechuic Acid and Protocatechuic Aldehyde: Old Wine in a New Bottle
title_fullStr	Antioxidant Effects of Protocatechuic Acid and Protocatechuic Aldehyde: Old Wine in a New Bottle
title_full_unstemmed	Antioxidant Effects of Protocatechuic Acid and Protocatechuic Aldehyde: Old Wine in a New Bottle
title_sort	antioxidant effects of protocatechuic acid and protocatechuic aldehyde: old wine in a new bottle
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/29980526642c44fca7b8048f536a4d5e
work_keys_str_mv	AT shijunzhang antioxidanteffectsofprotocatechuicacidandprotocatechuicaldehydeoldwineinanewbottle AT zhibogai antioxidanteffectsofprotocatechuicacidandprotocatechuicaldehydeoldwineinanewbottle AT tinggui antioxidanteffectsofprotocatechuicacidandprotocatechuicaldehydeoldwineinanewbottle AT juanlichen antioxidanteffectsofprotocatechuicacidandprotocatechuicaldehydeoldwineinanewbottle AT qingfachen antioxidanteffectsofprotocatechuicacidandprotocatechuicaldehydeoldwineinanewbottle AT yunlunli antioxidanteffectsofprotocatechuicacidandprotocatechuicaldehydeoldwineinanewbottle
_version_	1718418270469488640

Antioxidant Effects of Protocatechuic Acid and Protocatechuic Aldehyde: Old Wine in a New Bottle

Ejemplares similares