Role of oxidative stress and glutathione system in the pathogenesis of nonalcoholic fatty liver disease

In recent years nonalcoholic fatty liver disease transformed from uncommon clinical entity into common ailment along with alcoholic liver disease and viral hepatitis. Increase in the number of patients with nonalcoholic fatty liver disease is registered all over the world. Nevertheless the problem o...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: T. E. Promenasheva, L. S. Kolesnichenko, N. M. Kozlova
Formato: article
Lenguaje:RU
Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2014
Materias:
Q
Acceso en línea:https://doaj.org/article/29a01271ff0041fe85186dec307ea6f0
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:In recent years nonalcoholic fatty liver disease transformed from uncommon clinical entity into common ailment along with alcoholic liver disease and viral hepatitis. Increase in the number of patients with nonalcoholic fatty liver disease is registered all over the world. Nevertheless the problem of pathogenesis of nonalcoholic fatty liver disease is still discussable. Oxidative stress is of first importance in the development of hepatitis on the background of hepatic steatosis. Glutathione system is the main defender of cells from oxidative stress that can be used in the formation of new approaches to the treatment of nonalcoholic fatty liver disease.