Role of oxidative stress and glutathione system in the pathogenesis of nonalcoholic fatty liver disease

In recent years nonalcoholic fatty liver disease transformed from uncommon clinical entity into common ailment along with alcoholic liver disease and viral hepatitis. Increase in the number of patients with nonalcoholic fatty liver disease is registered all over the world. Nevertheless the problem o...

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Autores principales: T. E. Promenasheva, L. S. Kolesnichenko, N. M. Kozlova
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Lenguaje:RU
Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2014
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Acceso en línea:https://doaj.org/article/29a01271ff0041fe85186dec307ea6f0
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spelling oai:doaj.org-article:29a01271ff0041fe85186dec307ea6f02021-11-23T06:14:31ZRole of oxidative stress and glutathione system in the pathogenesis of nonalcoholic fatty liver disease2541-94202587-9596https://doaj.org/article/29a01271ff0041fe85186dec307ea6f02014-09-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1819https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596In recent years nonalcoholic fatty liver disease transformed from uncommon clinical entity into common ailment along with alcoholic liver disease and viral hepatitis. Increase in the number of patients with nonalcoholic fatty liver disease is registered all over the world. Nevertheless the problem of pathogenesis of nonalcoholic fatty liver disease is still discussable. Oxidative stress is of first importance in the development of hepatitis on the background of hepatic steatosis. Glutathione system is the main defender of cells from oxidative stress that can be used in the formation of new approaches to the treatment of nonalcoholic fatty liver disease.T. E. PromenashevaL. S. KolesnichenkoN. M. KozlovaScientific Сentre for Family Health and Human Reproduction Problemsarticlenonalcoholic fatty liver diseasehepatic steatosissteatohepatitisoxidative stressglutathioneScienceQRUActa Biomedica Scientifica, Vol 0, Iss 5, Pp 80-83 (2014)
institution DOAJ
collection DOAJ
language RU
topic nonalcoholic fatty liver disease
hepatic steatosis
steatohepatitis
oxidative stress
glutathione
Science
Q
spellingShingle nonalcoholic fatty liver disease
hepatic steatosis
steatohepatitis
oxidative stress
glutathione
Science
Q
T. E. Promenasheva
L. S. Kolesnichenko
N. M. Kozlova
Role of oxidative stress and glutathione system in the pathogenesis of nonalcoholic fatty liver disease
description In recent years nonalcoholic fatty liver disease transformed from uncommon clinical entity into common ailment along with alcoholic liver disease and viral hepatitis. Increase in the number of patients with nonalcoholic fatty liver disease is registered all over the world. Nevertheless the problem of pathogenesis of nonalcoholic fatty liver disease is still discussable. Oxidative stress is of first importance in the development of hepatitis on the background of hepatic steatosis. Glutathione system is the main defender of cells from oxidative stress that can be used in the formation of new approaches to the treatment of nonalcoholic fatty liver disease.
format article
author T. E. Promenasheva
L. S. Kolesnichenko
N. M. Kozlova
author_facet T. E. Promenasheva
L. S. Kolesnichenko
N. M. Kozlova
author_sort T. E. Promenasheva
title Role of oxidative stress and glutathione system in the pathogenesis of nonalcoholic fatty liver disease
title_short Role of oxidative stress and glutathione system in the pathogenesis of nonalcoholic fatty liver disease
title_full Role of oxidative stress and glutathione system in the pathogenesis of nonalcoholic fatty liver disease
title_fullStr Role of oxidative stress and glutathione system in the pathogenesis of nonalcoholic fatty liver disease
title_full_unstemmed Role of oxidative stress and glutathione system in the pathogenesis of nonalcoholic fatty liver disease
title_sort role of oxidative stress and glutathione system in the pathogenesis of nonalcoholic fatty liver disease
publisher Scientific Сentre for Family Health and Human Reproduction Problems
publishDate 2014
url https://doaj.org/article/29a01271ff0041fe85186dec307ea6f0
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AT lskolesnichenko roleofoxidativestressandglutathionesysteminthepathogenesisofnonalcoholicfattyliverdisease
AT nmkozlova roleofoxidativestressandglutathionesysteminthepathogenesisofnonalcoholicfattyliverdisease
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