Validity and reliability of the Health-Related Quality of Life Instrument with 8 Items (HINT-8) in Korean breast cancer patients

Objectives This study evaluated the validity and reliability of the Health-Related Quality of Life Instrument with 8 Items (HINT-8) in postoperative breast cancer patients in South Korea. Methods The study included 300 breast cancer patients visiting a tertiary hospital. We measured health-related q...

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Autores principales: Juyoung Kim, Min-Woo Jo, Hyeon-Jeong Lee, Sei-Hyun Ahn, Byung Ho Son, Jong Won Lee, Sae Byul Lee
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Publicado: Korea Centers for Disease Control & Prevention 2021
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Acceso en línea:https://doaj.org/article/29a7d0f83897465e9aa65738229d7aff
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spelling oai:doaj.org-article:29a7d0f83897465e9aa65738229d7aff2021-11-05T00:06:00ZValidity and reliability of the Health-Related Quality of Life Instrument with 8 Items (HINT-8) in Korean breast cancer patients2210-90992210-911010.24171/j.phrp.2021.0005https://doaj.org/article/29a7d0f83897465e9aa65738229d7aff2021-08-01T00:00:00Zhttp://ophrp.org/upload/pdf/j-phrp-2021-0005.pdfhttps://doaj.org/toc/2210-9099https://doaj.org/toc/2210-9110Objectives This study evaluated the validity and reliability of the Health-Related Quality of Life Instrument with 8 Items (HINT-8) in postoperative breast cancer patients in South Korea. Methods The study included 300 breast cancer patients visiting a tertiary hospital. We measured health-related quality of life (HRQoL) using the HINT-8, the 5-level EQ-5D version (EQ-5D-5L), and the Functional Assessment of Cancer Therapy-Breast (FACT-B). Discriminatory ability, known-group validity, and convergent validity were assessed. Reliability was evaluated with the Cohen kappa, weighted kappa, and intraclass correlation coefficient (ICC). Results The EQ-5D-5L indexes (p<0.001) and EQ visual analogue scale (VAS) scores (p<0.001) were significantly higher in subjects with no problems in each item of the HINT-8 than in those with problems. The FACT-B total scores were also higher in subjects without problems on the HINT-8. Older age, lower education level, and comorbidities were associated with a lower HINT-8 index. The HINT-8 index was correlated with the EQ-5D-5L index and the EQ VAS, with correlation coefficients of 0.671 (p<0.001) and 0.577 (p<0.001), respectively. The correlation coefficients between the HINT-8 and the FACT-B ranged from 0.390 to 0.714. The ICC was 0.690 (95% confidence interval, 0.580–0.780). Conclusion The HINT-8 showed appropriate validity for capturing HRQoL in postoperative breast cancer patients.Juyoung KimMin-Woo JoHyeon-Jeong LeeSei-Hyun AhnByung Ho SonJong Won LeeSae Byul LeeKorea Centers for Disease Control & Preventionarticlebreast neoplasmsquality of lifereproducibility of resultsSpecial situations and conditionsRC952-1245Infectious and parasitic diseasesRC109-216ENOsong Public Health and Research Perspectives, Vol 12, Iss 4, Pp 254-263 (2021)
institution DOAJ
collection DOAJ
language EN
topic breast neoplasms
quality of life
reproducibility of results
Special situations and conditions
RC952-1245
Infectious and parasitic diseases
RC109-216
spellingShingle breast neoplasms
quality of life
reproducibility of results
Special situations and conditions
RC952-1245
Infectious and parasitic diseases
RC109-216
Juyoung Kim
Min-Woo Jo
Hyeon-Jeong Lee
Sei-Hyun Ahn
Byung Ho Son
Jong Won Lee
Sae Byul Lee
Validity and reliability of the Health-Related Quality of Life Instrument with 8 Items (HINT-8) in Korean breast cancer patients
description Objectives This study evaluated the validity and reliability of the Health-Related Quality of Life Instrument with 8 Items (HINT-8) in postoperative breast cancer patients in South Korea. Methods The study included 300 breast cancer patients visiting a tertiary hospital. We measured health-related quality of life (HRQoL) using the HINT-8, the 5-level EQ-5D version (EQ-5D-5L), and the Functional Assessment of Cancer Therapy-Breast (FACT-B). Discriminatory ability, known-group validity, and convergent validity were assessed. Reliability was evaluated with the Cohen kappa, weighted kappa, and intraclass correlation coefficient (ICC). Results The EQ-5D-5L indexes (p<0.001) and EQ visual analogue scale (VAS) scores (p<0.001) were significantly higher in subjects with no problems in each item of the HINT-8 than in those with problems. The FACT-B total scores were also higher in subjects without problems on the HINT-8. Older age, lower education level, and comorbidities were associated with a lower HINT-8 index. The HINT-8 index was correlated with the EQ-5D-5L index and the EQ VAS, with correlation coefficients of 0.671 (p<0.001) and 0.577 (p<0.001), respectively. The correlation coefficients between the HINT-8 and the FACT-B ranged from 0.390 to 0.714. The ICC was 0.690 (95% confidence interval, 0.580–0.780). Conclusion The HINT-8 showed appropriate validity for capturing HRQoL in postoperative breast cancer patients.
format article
author Juyoung Kim
Min-Woo Jo
Hyeon-Jeong Lee
Sei-Hyun Ahn
Byung Ho Son
Jong Won Lee
Sae Byul Lee
author_facet Juyoung Kim
Min-Woo Jo
Hyeon-Jeong Lee
Sei-Hyun Ahn
Byung Ho Son
Jong Won Lee
Sae Byul Lee
author_sort Juyoung Kim
title Validity and reliability of the Health-Related Quality of Life Instrument with 8 Items (HINT-8) in Korean breast cancer patients
title_short Validity and reliability of the Health-Related Quality of Life Instrument with 8 Items (HINT-8) in Korean breast cancer patients
title_full Validity and reliability of the Health-Related Quality of Life Instrument with 8 Items (HINT-8) in Korean breast cancer patients
title_fullStr Validity and reliability of the Health-Related Quality of Life Instrument with 8 Items (HINT-8) in Korean breast cancer patients
title_full_unstemmed Validity and reliability of the Health-Related Quality of Life Instrument with 8 Items (HINT-8) in Korean breast cancer patients
title_sort validity and reliability of the health-related quality of life instrument with 8 items (hint-8) in korean breast cancer patients
publisher Korea Centers for Disease Control & Prevention
publishDate 2021
url https://doaj.org/article/29a7d0f83897465e9aa65738229d7aff
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