In situ cryo-electron tomography reveals gradient organization of ribosome biogenesis in intact nucleoli
The large and small subunits of the ribosome are synthesized independently within the nucleolus — a membrane-less compartment within the nucleus — before being exported into the cytoplasm. Here, the authors use in situ cryo-ET to observe ribosome maturation and reveal the native organization of the...
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Main Authors: | , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Subjects: | |
Online Access: | https://doaj.org/article/29af8d2ce12c4b48a297291bce32bf53 |
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