Toxicological analysis of acute pesticides poisoning among Moroccan population

The aim of this study is to evaluate the importance of toxicological analysis in acute intoxications by pesticides through the experience of the laboratory of the Poison Control and Pharmacovigilance Center of Morocco (CAPM). This is a retrospective study from January 2014 to September 2020, concern...

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Autores principales:	Birich Bouchra, El Hajjaji Souad, Ghandi Mohamed, Ait Daoud Naima, Ouaide Mustapha, Badrane Narjis, Soulaymani Bencheikh Rachida
Formato:	article
Lenguaje:	EN FR
Publicado:	EDP Sciences 2021
Materias:	Environmental sciences GE1-350
Acceso en línea:	https://doaj.org/article/29b05a3bbb874bda9f0f205d1ca592b7
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spelling	oai:doaj.org-article:29b05a3bbb874bda9f0f205d1ca592b72021-11-12T11:44:08ZToxicological analysis of acute pesticides poisoning among Moroccan population2267-124210.1051/e3sconf/202131901054https://doaj.org/article/29b05a3bbb874bda9f0f205d1ca592b72021-01-01T00:00:00Zhttps://www.e3s-conferences.org/articles/e3sconf/pdf/2021/95/e3sconf_vigisan_01054.pdfhttps://doaj.org/toc/2267-1242The aim of this study is to evaluate the importance of toxicological analysis in acute intoxications by pesticides through the experience of the laboratory of the Poison Control and Pharmacovigilance Center of Morocco (CAPM). This is a retrospective study from January 2014 to September 2020, concerning suspected pesticides poisoning cases. The cholinesterase activity was measured in whole blood and the chromatographic analyzes (GC-MS and LC-MS-MS) were conducted in blood, urine and gastric lavage fluid. In this study, 398 tests were involved. The median age of the patients was 14 with an interquartile range of [4-26 years]. The sex ratio (F / M) was 1.5. The requests were from the region of Rabat-Salé-Kénitra in 82.8% of cases (north-western Morocco). The cholinesterase activity measurement was performed for 295 patients with low values in 3.7% of cases. The toxicological screening by GC-MS and LC-MS-MS detected the pesticide responsible of poisoning in 62 cases as insecticides in 38% of cases, redenticides (33% of cases) and herbicides (5% of cases). Toxicological analysis plays an essential role in the diagnosis and the management of acute pesticides poisoning. Interpretation of results is carried over by analyst with close cooperation with clinical toxicologist.Birich BouchraEl Hajjaji SouadGhandi MohamedAit Daoud NaimaOuaide MustaphaBadrane NarjisSoulaymani Bencheikh RachidaEDP SciencesarticleEnvironmental sciencesGE1-350ENFRE3S Web of Conferences, Vol 319, p 01054 (2021)
institution	DOAJ
collection	DOAJ
language	EN FR
topic	Environmental sciences GE1-350
spellingShingle	Environmental sciences GE1-350 Birich Bouchra El Hajjaji Souad Ghandi Mohamed Ait Daoud Naima Ouaide Mustapha Badrane Narjis Soulaymani Bencheikh Rachida Toxicological analysis of acute pesticides poisoning among Moroccan population
description	The aim of this study is to evaluate the importance of toxicological analysis in acute intoxications by pesticides through the experience of the laboratory of the Poison Control and Pharmacovigilance Center of Morocco (CAPM). This is a retrospective study from January 2014 to September 2020, concerning suspected pesticides poisoning cases. The cholinesterase activity was measured in whole blood and the chromatographic analyzes (GC-MS and LC-MS-MS) were conducted in blood, urine and gastric lavage fluid. In this study, 398 tests were involved. The median age of the patients was 14 with an interquartile range of [4-26 years]. The sex ratio (F / M) was 1.5. The requests were from the region of Rabat-Salé-Kénitra in 82.8% of cases (north-western Morocco). The cholinesterase activity measurement was performed for 295 patients with low values in 3.7% of cases. The toxicological screening by GC-MS and LC-MS-MS detected the pesticide responsible of poisoning in 62 cases as insecticides in 38% of cases, redenticides (33% of cases) and herbicides (5% of cases). Toxicological analysis plays an essential role in the diagnosis and the management of acute pesticides poisoning. Interpretation of results is carried over by analyst with close cooperation with clinical toxicologist.
format	article
author	Birich Bouchra El Hajjaji Souad Ghandi Mohamed Ait Daoud Naima Ouaide Mustapha Badrane Narjis Soulaymani Bencheikh Rachida
author_facet	Birich Bouchra El Hajjaji Souad Ghandi Mohamed Ait Daoud Naima Ouaide Mustapha Badrane Narjis Soulaymani Bencheikh Rachida
author_sort	Birich Bouchra
title	Toxicological analysis of acute pesticides poisoning among Moroccan population
title_short	Toxicological analysis of acute pesticides poisoning among Moroccan population
title_full	Toxicological analysis of acute pesticides poisoning among Moroccan population
title_fullStr	Toxicological analysis of acute pesticides poisoning among Moroccan population
title_full_unstemmed	Toxicological analysis of acute pesticides poisoning among Moroccan population
title_sort	toxicological analysis of acute pesticides poisoning among moroccan population
publisher	EDP Sciences
publishDate	2021
url	https://doaj.org/article/29b05a3bbb874bda9f0f205d1ca592b7
work_keys_str_mv	AT birichbouchra toxicologicalanalysisofacutepesticidespoisoningamongmoroccanpopulation AT elhajjajisouad toxicologicalanalysisofacutepesticidespoisoningamongmoroccanpopulation AT ghandimohamed toxicologicalanalysisofacutepesticidespoisoningamongmoroccanpopulation AT aitdaoudnaima toxicologicalanalysisofacutepesticidespoisoningamongmoroccanpopulation AT ouaidemustapha toxicologicalanalysisofacutepesticidespoisoningamongmoroccanpopulation AT badranenarjis toxicologicalanalysisofacutepesticidespoisoningamongmoroccanpopulation AT soulaymanibencheikhrachida toxicologicalanalysisofacutepesticidespoisoningamongmoroccanpopulation
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Toxicological analysis of acute pesticides poisoning among Moroccan population

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