Supramolecular aptamer nano-constructs for receptor-mediated targeting and light-triggered release of chemotherapeutics into cancer cells

Effective therapeutic platforms should combine serum stability, selective targeting, and controlled drug release. Here, the authors self-assemble an aptamer-based nanoscaffold that contains separate cell-targeting and photo-regulated drug-carrying domains, realizing multiple therapeutic functionalit...

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Autores principales:	Deepak K. Prusty, Volker Adam, Reza M. Zadegan, Stephan Irsen, Michael Famulok
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/29b4ba7a1b2a46fe83630deece2fc4da
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spelling	oai:doaj.org-article:29b4ba7a1b2a46fe83630deece2fc4da2021-12-02T14:38:48ZSupramolecular aptamer nano-constructs for receptor-mediated targeting and light-triggered release of chemotherapeutics into cancer cells10.1038/s41467-018-02929-22041-1723https://doaj.org/article/29b4ba7a1b2a46fe83630deece2fc4da2018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-02929-2https://doaj.org/toc/2041-1723Effective therapeutic platforms should combine serum stability, selective targeting, and controlled drug release. Here, the authors self-assemble an aptamer-based nanoscaffold that contains separate cell-targeting and photo-regulated drug-carrying domains, realizing multiple therapeutic functionalities in a single construct.Deepak K. PrustyVolker AdamReza M. ZadeganStephan IrsenMichael FamulokNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Deepak K. Prusty Volker Adam Reza M. Zadegan Stephan Irsen Michael Famulok Supramolecular aptamer nano-constructs for receptor-mediated targeting and light-triggered release of chemotherapeutics into cancer cells
description	Effective therapeutic platforms should combine serum stability, selective targeting, and controlled drug release. Here, the authors self-assemble an aptamer-based nanoscaffold that contains separate cell-targeting and photo-regulated drug-carrying domains, realizing multiple therapeutic functionalities in a single construct.
format	article
author	Deepak K. Prusty Volker Adam Reza M. Zadegan Stephan Irsen Michael Famulok
author_facet	Deepak K. Prusty Volker Adam Reza M. Zadegan Stephan Irsen Michael Famulok
author_sort	Deepak K. Prusty
title	Supramolecular aptamer nano-constructs for receptor-mediated targeting and light-triggered release of chemotherapeutics into cancer cells
title_short	Supramolecular aptamer nano-constructs for receptor-mediated targeting and light-triggered release of chemotherapeutics into cancer cells
title_full	Supramolecular aptamer nano-constructs for receptor-mediated targeting and light-triggered release of chemotherapeutics into cancer cells
title_fullStr	Supramolecular aptamer nano-constructs for receptor-mediated targeting and light-triggered release of chemotherapeutics into cancer cells
title_full_unstemmed	Supramolecular aptamer nano-constructs for receptor-mediated targeting and light-triggered release of chemotherapeutics into cancer cells
title_sort	supramolecular aptamer nano-constructs for receptor-mediated targeting and light-triggered release of chemotherapeutics into cancer cells
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/29b4ba7a1b2a46fe83630deece2fc4da
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Supramolecular aptamer nano-constructs for receptor-mediated targeting and light-triggered release of chemotherapeutics into cancer cells

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