USP5 facilitates non-small cell lung cancer progression through stabilization of PD-L1

USP5 facilitates non-small cell lung cancer progression through stabilization of PD-L1

Abstract PD-L1(CD274) is a well-known immunosuppressive molecule, which confers immunoescape features to cancer cells and has become one of the major targets in cancer immunotherapies. Understanding the regulatory mechanisms that control PD-L1 protein expression is important for guiding immune check...

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Autores principales: Jinghua Pan, Yiting Qiao, Congcong Chen, Hongjing Zang, Xiaojing Zhang, Feng Qi, Cunjie Chang, Fan Yang, Mengqing Sun, Shengbin Lin, Quandong Tang, Lina Li, Menglan Wang, Minjie Wu, Yongzhu Liu, Caiyong Lai, Jianxiang Chen, Guo Chen
Formato: article
Lenguaje:EN
Publicado: Nature Publishing Group 2021
Materias:
Cytology
QH573-671
Acceso en línea:https://doaj.org/article/29b5d099a3ad4c68a7d6f7b7a805a2b5
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