The birth of a healthy child in the assisted reproductive technologies program after autologous co-culture of embryo with cumulus cells and a new CAT transfer technology. Case report

Cumulus cells are essential during oocytes growth and development, as well as during their maturation and fertilization. Research results have shown that embryo co-cultivation with autologous cumulus cells increases the frequency of blastocyst formation, and also improves the effectiveness of ART pr...

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Autores principales:	Gunai R. Asfarova, Veronika I. Smol'nikova, Natalia P. Makarova, Iuliia S. Drapkina, Anastasiia P. Sysoeva, Nataliia N. Lobanova, Elena A. Kalinina
Formato:	article
Lenguaje:	RU
Publicado:	IP Berlin A.V. 2021
Materias:	assisted reproductive technologies cumulus cells cat technology co-cultivation growth factors embryo oocyte embryo implantation recurrent implantation failure Gynecology and obstetrics RG1-991
Acceso en línea:	https://doaj.org/article/29b906aa830e470d9ae81e69ea73240e
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spelling	oai:doaj.org-article:29b906aa830e470d9ae81e69ea73240e2021-12-02T19:22:24ZThe birth of a healthy child in the assisted reproductive technologies program after autologous co-culture of embryo with cumulus cells and a new CAT transfer technology. Case report2079-56962079-583110.26442/20795696.2021.3.200876https://doaj.org/article/29b906aa830e470d9ae81e69ea73240e2021-08-01T00:00:00Zhttps://gynecology.orscience.ru/2079-5831/article/viewFile/76161/56755https://doaj.org/toc/2079-5696https://doaj.org/toc/2079-5831Cumulus cells are essential during oocytes growth and development, as well as during their maturation and fertilization. Research results have shown that embryo co-cultivation with autologous cumulus cells increases the frequency of blastocyst formation, and also improves the effectiveness of ART programs. Embryo transfer in such programs is recommended to be carried out using the CAT technology (Cumulus-Aided embryo Transfer), which includes embryo cultivation on a layer of cumulus cells and embryo transfer with a certain amount of diluted cumulus cells. Patient G., 38 years old, came to the department with infertility for 15 years and recurrent implantation failure in history. The patient had ART program with autologous co-cultivation of embryos with cumulus cells and a new CAT transfer technology. The patient fell pregnant and gave birth to a healthy child. Autologous cumulus cells can be a source of biologically active substances and improve embryological parameters and implantation rate in ART programs. Embryo co-cultivation with cumulus cells is especially important for patients with recurrent implantation failure. This technique can become an alternative for optimizing human embryos culturing.Gunai R. AsfarovaVeronika I. Smol'nikovaNatalia P. MakarovaIuliia S. DrapkinaAnastasiia P. SysoevaNataliia N. LobanovaElena A. KalininaIP Berlin A.V. articleassisted reproductive technologiescumulus cellscat technologyco-cultivationgrowth factorsembryooocyteembryo implantationrecurrent implantation failureGynecology and obstetricsRG1-991RUГинекология, Vol 23, Iss 3, Pp 270-274 (2021)
institution	DOAJ
collection	DOAJ
language	RU
topic	assisted reproductive technologies cumulus cells cat technology co-cultivation growth factors embryo oocyte embryo implantation recurrent implantation failure Gynecology and obstetrics RG1-991
spellingShingle	assisted reproductive technologies cumulus cells cat technology co-cultivation growth factors embryo oocyte embryo implantation recurrent implantation failure Gynecology and obstetrics RG1-991 Gunai R. Asfarova Veronika I. Smol'nikova Natalia P. Makarova Iuliia S. Drapkina Anastasiia P. Sysoeva Nataliia N. Lobanova Elena A. Kalinina The birth of a healthy child in the assisted reproductive technologies program after autologous co-culture of embryo with cumulus cells and a new CAT transfer technology. Case report
description	Cumulus cells are essential during oocytes growth and development, as well as during their maturation and fertilization. Research results have shown that embryo co-cultivation with autologous cumulus cells increases the frequency of blastocyst formation, and also improves the effectiveness of ART programs. Embryo transfer in such programs is recommended to be carried out using the CAT technology (Cumulus-Aided embryo Transfer), which includes embryo cultivation on a layer of cumulus cells and embryo transfer with a certain amount of diluted cumulus cells. Patient G., 38 years old, came to the department with infertility for 15 years and recurrent implantation failure in history. The patient had ART program with autologous co-cultivation of embryos with cumulus cells and a new CAT transfer technology. The patient fell pregnant and gave birth to a healthy child. Autologous cumulus cells can be a source of biologically active substances and improve embryological parameters and implantation rate in ART programs. Embryo co-cultivation with cumulus cells is especially important for patients with recurrent implantation failure. This technique can become an alternative for optimizing human embryos culturing.
format	article
author	Gunai R. Asfarova Veronika I. Smol'nikova Natalia P. Makarova Iuliia S. Drapkina Anastasiia P. Sysoeva Nataliia N. Lobanova Elena A. Kalinina
author_facet	Gunai R. Asfarova Veronika I. Smol'nikova Natalia P. Makarova Iuliia S. Drapkina Anastasiia P. Sysoeva Nataliia N. Lobanova Elena A. Kalinina
author_sort	Gunai R. Asfarova
title	The birth of a healthy child in the assisted reproductive technologies program after autologous co-culture of embryo with cumulus cells and a new CAT transfer technology. Case report
title_short	The birth of a healthy child in the assisted reproductive technologies program after autologous co-culture of embryo with cumulus cells and a new CAT transfer technology. Case report
title_full	The birth of a healthy child in the assisted reproductive technologies program after autologous co-culture of embryo with cumulus cells and a new CAT transfer technology. Case report
title_fullStr	The birth of a healthy child in the assisted reproductive technologies program after autologous co-culture of embryo with cumulus cells and a new CAT transfer technology. Case report
title_full_unstemmed	The birth of a healthy child in the assisted reproductive technologies program after autologous co-culture of embryo with cumulus cells and a new CAT transfer technology. Case report
title_sort	birth of a healthy child in the assisted reproductive technologies program after autologous co-culture of embryo with cumulus cells and a new cat transfer technology. case report
publisher	IP Berlin A.V.
publishDate	2021
url	https://doaj.org/article/29b906aa830e470d9ae81e69ea73240e
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The birth of a healthy child in the assisted reproductive technologies program after autologous co-culture of embryo with cumulus cells and a new CAT transfer technology. Case report

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