TSLP is a direct trigger for T cell migration in filaggrin-deficient skin equivalents

TSLP is a direct trigger for T cell migration in filaggrin-deficient skin equivalents

Abstract Mutations in the gene encoding for filaggrin (FLG) are major predisposing factors for atopic dermatitis (AD). Besides genetic predisposition, immunological dysregulations considerably contribute to its pathophysiology. For example, thymic stromal lymphopoietin (TSLP) is highly expressed in...

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Main Authors: Leonie Wallmeyer, Kristina Dietert, Michaela Sochorová, Achim D. Gruber, Burkhard Kleuser, Kateřina Vávrová, Sarah Hedtrich
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/29bafae408b546e38cc4fe0bf4395f17
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