β2-Adrenergic ion-channel coupled receptors as conformational motion detectors.
Ion Channel-Coupled Receptors (ICCRs) are artificial proteins comprised of a G protein-coupled receptor and a fused ion channel, engineered to couple channel gating to ligand binding. These novel biological objects have potential use in drug screening and functional characterization, in addition to...
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Auteurs principaux: | , , , |
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2011
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Accès en ligne: | https://doaj.org/article/29bc49e328c94fd691ad1071f53c93b9 |
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