Programmed hierarchical patterning of bacterial populations

Biological self-organization uses hierarchical induction of gene expression but this has not been exploited by synthetic biology. Here the authors use an AND gate based on a split T7 RNA polymerase to organize programmed hierarchical patterning of gene expression across a bacterial population.

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Autores principales: Christian R. Boehm, Paul K. Grant, Jim Haseloff
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/29c2075fafe3452289868203408afa1d
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spelling oai:doaj.org-article:29c2075fafe3452289868203408afa1d2021-12-02T16:50:06ZProgrammed hierarchical patterning of bacterial populations10.1038/s41467-018-03069-32041-1723https://doaj.org/article/29c2075fafe3452289868203408afa1d2018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03069-3https://doaj.org/toc/2041-1723Biological self-organization uses hierarchical induction of gene expression but this has not been exploited by synthetic biology. Here the authors use an AND gate based on a split T7 RNA polymerase to organize programmed hierarchical patterning of gene expression across a bacterial population.Christian R. BoehmPaul K. GrantJim HaseloffNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Christian R. Boehm
Paul K. Grant
Jim Haseloff
Programmed hierarchical patterning of bacterial populations
description Biological self-organization uses hierarchical induction of gene expression but this has not been exploited by synthetic biology. Here the authors use an AND gate based on a split T7 RNA polymerase to organize programmed hierarchical patterning of gene expression across a bacterial population.
format article
author Christian R. Boehm
Paul K. Grant
Jim Haseloff
author_facet Christian R. Boehm
Paul K. Grant
Jim Haseloff
author_sort Christian R. Boehm
title Programmed hierarchical patterning of bacterial populations
title_short Programmed hierarchical patterning of bacterial populations
title_full Programmed hierarchical patterning of bacterial populations
title_fullStr Programmed hierarchical patterning of bacterial populations
title_full_unstemmed Programmed hierarchical patterning of bacterial populations
title_sort programmed hierarchical patterning of bacterial populations
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/29c2075fafe3452289868203408afa1d
work_keys_str_mv AT christianrboehm programmedhierarchicalpatterningofbacterialpopulations
AT paulkgrant programmedhierarchicalpatterningofbacterialpopulations
AT jimhaseloff programmedhierarchicalpatterningofbacterialpopulations
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