SARS-CoV-2-specific T cell memory is sustained in COVID-19 convalescent patients for 10 months with successful development of stem cell-like memory T cells

T cells are instrumental to protective immune responses against SARS-CoV-2, the pathogen responsible for the COVID-19 pandemic. Here the authors show that, in convalescent COVID-19 patients, memory T cell responses are detectable up to 317 days post-symptom onset, in which the presence of stem cell-...

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Autores principales:	Jae Hyung Jung, Min-Seok Rha, Moa Sa, Hee Kyoung Choi, Ji Hoon Jeon, Hyeri Seok, Dae Won Park, Su-Hyung Park, Hye Won Jeong, Won Suk Choi, Eui-Cheol Shin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/29c2c2d85ebd46cba6db44a906fe541f
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spelling	oai:doaj.org-article:29c2c2d85ebd46cba6db44a906fe541f2021-12-02T18:19:01ZSARS-CoV-2-specific T cell memory is sustained in COVID-19 convalescent patients for 10 months with successful development of stem cell-like memory T cells10.1038/s41467-021-24377-12041-1723https://doaj.org/article/29c2c2d85ebd46cba6db44a906fe541f2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24377-1https://doaj.org/toc/2041-1723T cells are instrumental to protective immune responses against SARS-CoV-2, the pathogen responsible for the COVID-19 pandemic. Here the authors show that, in convalescent COVID-19 patients, memory T cell responses are detectable up to 317 days post-symptom onset, in which the presence of stem cell-like memory T cells further hints long-lasting immunity.Jae Hyung JungMin-Seok RhaMoa SaHee Kyoung ChoiJi Hoon JeonHyeri SeokDae Won ParkSu-Hyung ParkHye Won JeongWon Suk ChoiEui-Cheol ShinNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jae Hyung Jung Min-Seok Rha Moa Sa Hee Kyoung Choi Ji Hoon Jeon Hyeri Seok Dae Won Park Su-Hyung Park Hye Won Jeong Won Suk Choi Eui-Cheol Shin SARS-CoV-2-specific T cell memory is sustained in COVID-19 convalescent patients for 10 months with successful development of stem cell-like memory T cells
description	T cells are instrumental to protective immune responses against SARS-CoV-2, the pathogen responsible for the COVID-19 pandemic. Here the authors show that, in convalescent COVID-19 patients, memory T cell responses are detectable up to 317 days post-symptom onset, in which the presence of stem cell-like memory T cells further hints long-lasting immunity.
format	article
author	Jae Hyung Jung Min-Seok Rha Moa Sa Hee Kyoung Choi Ji Hoon Jeon Hyeri Seok Dae Won Park Su-Hyung Park Hye Won Jeong Won Suk Choi Eui-Cheol Shin
author_facet	Jae Hyung Jung Min-Seok Rha Moa Sa Hee Kyoung Choi Ji Hoon Jeon Hyeri Seok Dae Won Park Su-Hyung Park Hye Won Jeong Won Suk Choi Eui-Cheol Shin
author_sort	Jae Hyung Jung
title	SARS-CoV-2-specific T cell memory is sustained in COVID-19 convalescent patients for 10 months with successful development of stem cell-like memory T cells
title_short	SARS-CoV-2-specific T cell memory is sustained in COVID-19 convalescent patients for 10 months with successful development of stem cell-like memory T cells
title_full	SARS-CoV-2-specific T cell memory is sustained in COVID-19 convalescent patients for 10 months with successful development of stem cell-like memory T cells
title_fullStr	SARS-CoV-2-specific T cell memory is sustained in COVID-19 convalescent patients for 10 months with successful development of stem cell-like memory T cells
title_full_unstemmed	SARS-CoV-2-specific T cell memory is sustained in COVID-19 convalescent patients for 10 months with successful development of stem cell-like memory T cells
title_sort	sars-cov-2-specific t cell memory is sustained in covid-19 convalescent patients for 10 months with successful development of stem cell-like memory t cells
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/29c2c2d85ebd46cba6db44a906fe541f
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SARS-CoV-2-specific T cell memory is sustained in COVID-19 convalescent patients for 10 months with successful development of stem cell-like memory T cells

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