Integrated Bioinformatic and Targeted Deletion Analyses of the SRS Gene Superfamily Identify SRS29C as a Negative Regulator of <italic toggle="yes">Toxoplasma</italic> Virulence

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Integrated Bioinformatic and Targeted Deletion Analyses of the SRS Gene Superfamily Identify SRS29C as a Negative Regulator of <italic toggle="yes">Toxoplasma</italic> Virulence

ABSTRACT The Toxoplasma gondii SRS gene superfamily is structurally related to SRS29B (formerly SAG1), a surface adhesin that binds host cells and stimulates host immunity. Comparative genomic analyses of three Toxoplasma strains identified 182 SRS genes distributed across 14 chromosomes at 57 genom...

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Autores principales:	James D. Wasmuth, Viviana Pszenny, Simon Haile, Emily M. Jansen, Alexandra T. Gast, Alan Sher, Jon P. Boyle, Martin J. Boulanger, John Parkinson, Michael E. Grigg
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2012
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/29c657891aca450c82653a06a7d1225a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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