Evaluation of 30 DNA damage response and 6 mismatch repair gene mutations as biomarkers for immunotherapy outcomes across multiple solid tumor types

Objective: DNA damage response (DDR) genes have low mutation rates, which may restrict their clinical applications in predicting the outcomes of immune checkpoint inhibitor (ICI) treatment. Thus, a systemic analysis of multiple DDR genes is needed to identify potential biomarkers of ICI efficacy. Me...

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Bibliographic Details
Main Authors: Zhe Gong, Yue Yang, Jieyun Zhang, Weijian Guo
Format: article
Language:EN
Published: China Anti-Cancer Association 2021
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Online Access:https://doaj.org/article/29cb4935ee744defb0f69f530c0874a9
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