Evaluation of 30 DNA damage response and 6 mismatch repair gene mutations as biomarkers for immunotherapy outcomes across multiple solid tumor types
Objective: DNA damage response (DDR) genes have low mutation rates, which may restrict their clinical applications in predicting the outcomes of immune checkpoint inhibitor (ICI) treatment. Thus, a systemic analysis of multiple DDR genes is needed to identify potential biomarkers of ICI efficacy. Me...
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Main Authors: | Zhe Gong, Yue Yang, Jieyun Zhang, Weijian Guo |
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Format: | article |
Language: | EN |
Published: |
China Anti-Cancer Association
2021
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Online Access: | https://doaj.org/article/29cb4935ee744defb0f69f530c0874a9 |
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