The potential of understorey plants from Gunung Gede Pangrango National Park (West Java, Indonesia) as cervixs anticancer agents

Abstract. Arbiastutie Y, Marsono Dj, Hartati MS, Purwanto R. 2017. The potential of understorey plants from Gunung Gede Pangrango National Park (West Java, Indonesia) as cervixs anticancer agents. Biodiversitas 18: 109-115. This study aims to screening 97 species obtained from the understorey plants...

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Autores principales: YANIETA ARBIASTUTIE, DJOKO MARSONO, MAE SRI HARTATI, RISHADI PURWANTO
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Publicado: MBI & UNS Solo 2017
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spelling oai:doaj.org-article:29d4036b98b34919821933f6b93a81762021-11-16T13:50:45ZThe potential of understorey plants from Gunung Gede Pangrango National Park (West Java, Indonesia) as cervixs anticancer agents1412-033X2085-472210.13057/biodiv/d180115https://doaj.org/article/29d4036b98b34919821933f6b93a81762017-02-01T00:00:00Zhttps://smujo.id/biodiv/article/view/758https://doaj.org/toc/1412-033Xhttps://doaj.org/toc/2085-4722Abstract. Arbiastutie Y, Marsono Dj, Hartati MS, Purwanto R. 2017. The potential of understorey plants from Gunung Gede Pangrango National Park (West Java, Indonesia) as cervixs anticancer agents. Biodiversitas 18: 109-115. This study aims to screening 97 species obtained from the understorey plants of The Gunung Gede Pangrango National Park of West Java, Indonesia as the anticancer cervixs agents. The anticancer plant activity is determined by the cytotoxicity assay of understorey plant methanol extracts against HeLa cervixs cancer cells using MTT test method. IC50 which is an indicator of cytotoxicity is determined by the probit analysis. The results show that of the 97 plants tested, there are five potential anticancer plants i.e. Physalis peruvianaL. (Solanaceae), Tithonia diversifolia (Hemsl.) A. Gray (Asteraceae), Lantana camara L. (Verbenaceae), Clidema hirta (L). D.Don (Lamiaceae), and Solanum torvum Sw (Solananceae) with IC50 values of 67.85 µg/mL, 3.38 µg/mL, 43.54 µg/mL, 36.93 µg/mL, and 59.09 µg/mL respectively. The phytochemical compound find five understorey plants consisting of alkaloids, steroids, terpenoids, phenol, flavonoids and tannin. Keywords: Anticancer, Gunung Gede Pangrango National Park, HeLa, MTT assay, understorey plantYANIETA ARBIASTUTIEDJOKO MARSONOMAE SRI HARTATIRISHADI PURWANTOMBI & UNS Soloarticleanticancer, gunung gede pangrango national park, hela, mtt assay, understorey plantBiology (General)QH301-705.5ENBiodiversitas, Vol 18, Iss 1 (2017)
institution DOAJ
collection DOAJ
language EN
topic anticancer, gunung gede pangrango national park, hela, mtt assay, understorey plant
Biology (General)
QH301-705.5
spellingShingle anticancer, gunung gede pangrango national park, hela, mtt assay, understorey plant
Biology (General)
QH301-705.5
YANIETA ARBIASTUTIE
DJOKO MARSONO
MAE SRI HARTATI
RISHADI PURWANTO
The potential of understorey plants from Gunung Gede Pangrango National Park (West Java, Indonesia) as cervixs anticancer agents
description Abstract. Arbiastutie Y, Marsono Dj, Hartati MS, Purwanto R. 2017. The potential of understorey plants from Gunung Gede Pangrango National Park (West Java, Indonesia) as cervixs anticancer agents. Biodiversitas 18: 109-115. This study aims to screening 97 species obtained from the understorey plants of The Gunung Gede Pangrango National Park of West Java, Indonesia as the anticancer cervixs agents. The anticancer plant activity is determined by the cytotoxicity assay of understorey plant methanol extracts against HeLa cervixs cancer cells using MTT test method. IC50 which is an indicator of cytotoxicity is determined by the probit analysis. The results show that of the 97 plants tested, there are five potential anticancer plants i.e. Physalis peruvianaL. (Solanaceae), Tithonia diversifolia (Hemsl.) A. Gray (Asteraceae), Lantana camara L. (Verbenaceae), Clidema hirta (L). D.Don (Lamiaceae), and Solanum torvum Sw (Solananceae) with IC50 values of 67.85 µg/mL, 3.38 µg/mL, 43.54 µg/mL, 36.93 µg/mL, and 59.09 µg/mL respectively. The phytochemical compound find five understorey plants consisting of alkaloids, steroids, terpenoids, phenol, flavonoids and tannin. Keywords: Anticancer, Gunung Gede Pangrango National Park, HeLa, MTT assay, understorey plant
format article
author YANIETA ARBIASTUTIE
DJOKO MARSONO
MAE SRI HARTATI
RISHADI PURWANTO
author_facet YANIETA ARBIASTUTIE
DJOKO MARSONO
MAE SRI HARTATI
RISHADI PURWANTO
author_sort YANIETA ARBIASTUTIE
title The potential of understorey plants from Gunung Gede Pangrango National Park (West Java, Indonesia) as cervixs anticancer agents
title_short The potential of understorey plants from Gunung Gede Pangrango National Park (West Java, Indonesia) as cervixs anticancer agents
title_full The potential of understorey plants from Gunung Gede Pangrango National Park (West Java, Indonesia) as cervixs anticancer agents
title_fullStr The potential of understorey plants from Gunung Gede Pangrango National Park (West Java, Indonesia) as cervixs anticancer agents
title_full_unstemmed The potential of understorey plants from Gunung Gede Pangrango National Park (West Java, Indonesia) as cervixs anticancer agents
title_sort potential of understorey plants from gunung gede pangrango national park (west java, indonesia) as cervixs anticancer agents
publisher MBI & UNS Solo
publishDate 2017
url https://doaj.org/article/29d4036b98b34919821933f6b93a8176
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