Brain activity regulates loose coupling between mitochondrial and cytosolic Ca2+ transients

Mitochondrial calcium signaling plays an important role in neuronal bioenergetics yet its regulation by brain activity in vivo is not understood. Here, the authors show that mitochondrial and cytosolic calcium transients are dynamically coupled as a function of brain activity.

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Autores principales:	Yuan Lin, Lin-Lin Li, Wei Nie, Xiaolei Liu, Avital Adler, Chi Xiao, Fujian Lu, Liping Wang, Hua Han, Xianhua Wang, Wen-Biao Gan, Heping Cheng
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/29d6d5edd7164898ae9ffc3ca5668d1c
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spelling	oai:doaj.org-article:29d6d5edd7164898ae9ffc3ca5668d1c2021-12-02T15:35:48ZBrain activity regulates loose coupling between mitochondrial and cytosolic Ca2+ transients10.1038/s41467-019-13142-02041-1723https://doaj.org/article/29d6d5edd7164898ae9ffc3ca5668d1c2019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13142-0https://doaj.org/toc/2041-1723Mitochondrial calcium signaling plays an important role in neuronal bioenergetics yet its regulation by brain activity in vivo is not understood. Here, the authors show that mitochondrial and cytosolic calcium transients are dynamically coupled as a function of brain activity.Yuan LinLin-Lin LiWei NieXiaolei LiuAvital AdlerChi XiaoFujian LuLiping WangHua HanXianhua WangWen-Biao GanHeping ChengNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yuan Lin Lin-Lin Li Wei Nie Xiaolei Liu Avital Adler Chi Xiao Fujian Lu Liping Wang Hua Han Xianhua Wang Wen-Biao Gan Heping Cheng Brain activity regulates loose coupling between mitochondrial and cytosolic Ca2+ transients
description	Mitochondrial calcium signaling plays an important role in neuronal bioenergetics yet its regulation by brain activity in vivo is not understood. Here, the authors show that mitochondrial and cytosolic calcium transients are dynamically coupled as a function of brain activity.
format	article
author	Yuan Lin Lin-Lin Li Wei Nie Xiaolei Liu Avital Adler Chi Xiao Fujian Lu Liping Wang Hua Han Xianhua Wang Wen-Biao Gan Heping Cheng
author_facet	Yuan Lin Lin-Lin Li Wei Nie Xiaolei Liu Avital Adler Chi Xiao Fujian Lu Liping Wang Hua Han Xianhua Wang Wen-Biao Gan Heping Cheng
author_sort	Yuan Lin
title	Brain activity regulates loose coupling between mitochondrial and cytosolic Ca2+ transients
title_short	Brain activity regulates loose coupling between mitochondrial and cytosolic Ca2+ transients
title_full	Brain activity regulates loose coupling between mitochondrial and cytosolic Ca2+ transients
title_fullStr	Brain activity regulates loose coupling between mitochondrial and cytosolic Ca2+ transients
title_full_unstemmed	Brain activity regulates loose coupling between mitochondrial and cytosolic Ca2+ transients
title_sort	brain activity regulates loose coupling between mitochondrial and cytosolic ca2+ transients
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/29d6d5edd7164898ae9ffc3ca5668d1c
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Brain activity regulates loose coupling between mitochondrial and cytosolic Ca2+ transients

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