Mitochondrial levels determine variability in cell death by modulating apoptotic gene expression
It is unclear what causes variation in cell death in response to chemotherapy. Here, the authors show that cellular mitochondrial content modulates apoptotic protein levels, which in turn regulates response to agents such as TRAIL.
Guardado en:
Autores principales: | Silvia Márquez-Jurado, Juan Díaz-Colunga, Ricardo Pires das Neves, Antonio Martinez-Lorente, Fernando Almazán, Raúl Guantes, Francisco J. Iborra |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/29db1d8ce1734f508ff800f6141230b0 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Connecting variability in global transcription rate to mitochondrial variability.
por: Ricardo Pires das Neves, et al.
Publicado: (2010) -
Mitochondrial variability as a source of extrinsic cellular noise.
por: Iain G Johnston, et al.
Publicado: (2012) -
Osmotic modulation of chromatin impacts on efficiency and kinetics of cell fate modulation
por: A. F. Lima, et al.
Publicado: (2018) -
Genes of the mitochondrial apoptotic pathway in Mytilus galloprovincialis.
por: Noelia Estévez-Calvar, et al.
Publicado: (2013) -
HO-3867 Induces ROS-Dependent Stress Response and Apoptotic Cell Death in Leishmania donovani
por: Amrita Das, et al.
Publicado: (2021)