Chronic neuronal activation increases dynamic microtubules to enhance functional axon regeneration after dorsal root crush injury
Central axons have limited regenerative ability following injury. Here, the authors show that chronic activation of DRG neurons results in highly dynamic microtubules at the distal axons and enhanced axonal regrowth and synaptogenesis in the spinal cord affecting functional recovery.
Guardado en:
Autores principales: | Di Wu, Ying Jin, Tatiana M. Shapiro, Abhishek Hinduja, Peter W. Baas, Veronica J. Tom |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/29dfd0fe65224658b1b222872c7de523 |
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