Undulation of a moving fluid membrane pushed by filament growth

Abstract Biomembranes experience out-of-equilibrium conditions in living cells. Their undulation spectra are different from those in thermal equilibrium. Here, we report on the undulation of a fluid membrane pushed by the stepwise growth of filaments as in the leading edge of migrating cells, using...

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Autores principales:	Hiroshi Noguchi, Olivier Pierre-Louis
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/29e0318c14224befbbbce22471b5f87b
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spelling	oai:doaj.org-article:29e0318c14224befbbbce22471b5f87b2021-12-02T15:51:14ZUndulation of a moving fluid membrane pushed by filament growth10.1038/s41598-021-87073-62045-2322https://doaj.org/article/29e0318c14224befbbbce22471b5f87b2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-87073-6https://doaj.org/toc/2045-2322Abstract Biomembranes experience out-of-equilibrium conditions in living cells. Their undulation spectra are different from those in thermal equilibrium. Here, we report on the undulation of a fluid membrane pushed by the stepwise growth of filaments as in the leading edge of migrating cells, using three-dimensional Monte Carlo simulations. The undulations are largely modified from equilibrium behavior. When the tension is constrained, the low-wave-number modes are suppressed or enhanced at small or large growth step sizes, respectively, for high membrane surface tensions. In contrast, they are always suppressed for the tensionless membrane, wherein the wave-number range of the suppression depends on the step size. When the membrane area is constrained, in addition to these features, a specific mode is excited for zero and low surface tensions. The reduction of the undulation first induces membrane buckling at the lowest wave-number, and subsequently, other modes are excited, leading to a steady state.Hiroshi NoguchiOlivier Pierre-LouisNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Hiroshi Noguchi Olivier Pierre-Louis Undulation of a moving fluid membrane pushed by filament growth
description	Abstract Biomembranes experience out-of-equilibrium conditions in living cells. Their undulation spectra are different from those in thermal equilibrium. Here, we report on the undulation of a fluid membrane pushed by the stepwise growth of filaments as in the leading edge of migrating cells, using three-dimensional Monte Carlo simulations. The undulations are largely modified from equilibrium behavior. When the tension is constrained, the low-wave-number modes are suppressed or enhanced at small or large growth step sizes, respectively, for high membrane surface tensions. In contrast, they are always suppressed for the tensionless membrane, wherein the wave-number range of the suppression depends on the step size. When the membrane area is constrained, in addition to these features, a specific mode is excited for zero and low surface tensions. The reduction of the undulation first induces membrane buckling at the lowest wave-number, and subsequently, other modes are excited, leading to a steady state.
format	article
author	Hiroshi Noguchi Olivier Pierre-Louis
author_facet	Hiroshi Noguchi Olivier Pierre-Louis
author_sort	Hiroshi Noguchi
title	Undulation of a moving fluid membrane pushed by filament growth
title_short	Undulation of a moving fluid membrane pushed by filament growth
title_full	Undulation of a moving fluid membrane pushed by filament growth
title_fullStr	Undulation of a moving fluid membrane pushed by filament growth
title_full_unstemmed	Undulation of a moving fluid membrane pushed by filament growth
title_sort	undulation of a moving fluid membrane pushed by filament growth
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/29e0318c14224befbbbce22471b5f87b
work_keys_str_mv	AT hiroshinoguchi undulationofamovingfluidmembranepushedbyfilamentgrowth AT olivierpierrelouis undulationofamovingfluidmembranepushedbyfilamentgrowth
_version_	1718385621133688832

Undulation of a moving fluid membrane pushed by filament growth

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