Engineering modular intracellular protein sensor-actuator devices
Synthetic biology principles are often used to design circuits that tune gene expression in response to changes in intracellular environments. Here the authors design a modular platform for intracellular protein sensing devices with transcriptional output.
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Nature Portfolio
2018
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oai:doaj.org-article:29e185b3e05642a993be2f596425ebc82021-12-02T16:49:34ZEngineering modular intracellular protein sensor-actuator devices10.1038/s41467-018-03984-52041-1723https://doaj.org/article/29e185b3e05642a993be2f596425ebc82018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03984-5https://doaj.org/toc/2041-1723Synthetic biology principles are often used to design circuits that tune gene expression in response to changes in intracellular environments. Here the authors design a modular platform for intracellular protein sensing devices with transcriptional output.Velia SicilianoBreanna DiAndrethBlandine MonelJacob BealJin HuhKiera L ClaytonLiliana WroblewskaAnneMarie McKeonBruce D. WalkerRon WeissNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-7 (2018) |
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Science Q Velia Siciliano Breanna DiAndreth Blandine Monel Jacob Beal Jin Huh Kiera L Clayton Liliana Wroblewska AnneMarie McKeon Bruce D. Walker Ron Weiss Engineering modular intracellular protein sensor-actuator devices |
description |
Synthetic biology principles are often used to design circuits that tune gene expression in response to changes in intracellular environments. Here the authors design a modular platform for intracellular protein sensing devices with transcriptional output. |
format |
article |
author |
Velia Siciliano Breanna DiAndreth Blandine Monel Jacob Beal Jin Huh Kiera L Clayton Liliana Wroblewska AnneMarie McKeon Bruce D. Walker Ron Weiss |
author_facet |
Velia Siciliano Breanna DiAndreth Blandine Monel Jacob Beal Jin Huh Kiera L Clayton Liliana Wroblewska AnneMarie McKeon Bruce D. Walker Ron Weiss |
author_sort |
Velia Siciliano |
title |
Engineering modular intracellular protein sensor-actuator devices |
title_short |
Engineering modular intracellular protein sensor-actuator devices |
title_full |
Engineering modular intracellular protein sensor-actuator devices |
title_fullStr |
Engineering modular intracellular protein sensor-actuator devices |
title_full_unstemmed |
Engineering modular intracellular protein sensor-actuator devices |
title_sort |
engineering modular intracellular protein sensor-actuator devices |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/29e185b3e05642a993be2f596425ebc8 |
work_keys_str_mv |
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1718383267165503488 |