Limited window for donation of convalescent plasma with high live-virus neutralizing antibody titers for COVID-19 immunotherapy

Gontu et al. conducted a longitudinal study in COVID patients in which they assessed the response trajectories of antibodies directed to the SARS-CoV-2 surface spike glycoprotein and in vitro SARS-CoV-2 live virus neutralizing titers. Their measurements demonstrate the presence of an optimum window...

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Autores principales: Abhinay Gontu, Sreenidhi Srinivasan, Eric Salazar, Meera Surendran Nair, Ruth H. Nissly, Denver Greenawalt, Ian M. Bird, Catherine M. Herzog, Matthew J. Ferrari, Indira Poojary, Robab Katani, Scott E. Lindner, Allen M. Minns, Randall Rossi, Paul A. Christensen, Brian Castillo, Jian Chen, Todd N. Eagar, Xin Yi, Picheng Zhao, Christopher Leveque, Randall J. Olsen, David W. Bernard, Jimmy Gollihar, Suresh V. Kuchipudi, James M. Musser, Vivek Kapur
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/29e9d16320ed452bba1c23cd05a61b50
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spelling oai:doaj.org-article:29e9d16320ed452bba1c23cd05a61b502021-12-02T13:34:56ZLimited window for donation of convalescent plasma with high live-virus neutralizing antibody titers for COVID-19 immunotherapy10.1038/s42003-021-01813-y2399-3642https://doaj.org/article/29e9d16320ed452bba1c23cd05a61b502021-02-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01813-yhttps://doaj.org/toc/2399-3642Gontu et al. conducted a longitudinal study in COVID patients in which they assessed the response trajectories of antibodies directed to the SARS-CoV-2 surface spike glycoprotein and in vitro SARS-CoV-2 live virus neutralizing titers. Their measurements demonstrate the presence of an optimum window for convalescent plasma donation as well as predictions of the most suitable donor type.Abhinay GontuSreenidhi SrinivasanEric SalazarMeera Surendran NairRuth H. NisslyDenver GreenawaltIan M. BirdCatherine M. HerzogMatthew J. FerrariIndira PoojaryRobab KataniScott E. LindnerAllen M. MinnsRandall RossiPaul A. ChristensenBrian CastilloJian ChenTodd N. EagarXin YiPicheng ZhaoChristopher LevequeRandall J. OlsenDavid W. BernardJimmy GolliharSuresh V. KuchipudiJames M. MusserVivek KapurNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Abhinay Gontu
Sreenidhi Srinivasan
Eric Salazar
Meera Surendran Nair
Ruth H. Nissly
Denver Greenawalt
Ian M. Bird
Catherine M. Herzog
Matthew J. Ferrari
Indira Poojary
Robab Katani
Scott E. Lindner
Allen M. Minns
Randall Rossi
Paul A. Christensen
Brian Castillo
Jian Chen
Todd N. Eagar
Xin Yi
Picheng Zhao
Christopher Leveque
Randall J. Olsen
David W. Bernard
Jimmy Gollihar
Suresh V. Kuchipudi
James M. Musser
Vivek Kapur
Limited window for donation of convalescent plasma with high live-virus neutralizing antibody titers for COVID-19 immunotherapy
description Gontu et al. conducted a longitudinal study in COVID patients in which they assessed the response trajectories of antibodies directed to the SARS-CoV-2 surface spike glycoprotein and in vitro SARS-CoV-2 live virus neutralizing titers. Their measurements demonstrate the presence of an optimum window for convalescent plasma donation as well as predictions of the most suitable donor type.
format article
author Abhinay Gontu
Sreenidhi Srinivasan
Eric Salazar
Meera Surendran Nair
Ruth H. Nissly
Denver Greenawalt
Ian M. Bird
Catherine M. Herzog
Matthew J. Ferrari
Indira Poojary
Robab Katani
Scott E. Lindner
Allen M. Minns
Randall Rossi
Paul A. Christensen
Brian Castillo
Jian Chen
Todd N. Eagar
Xin Yi
Picheng Zhao
Christopher Leveque
Randall J. Olsen
David W. Bernard
Jimmy Gollihar
Suresh V. Kuchipudi
James M. Musser
Vivek Kapur
author_facet Abhinay Gontu
Sreenidhi Srinivasan
Eric Salazar
Meera Surendran Nair
Ruth H. Nissly
Denver Greenawalt
Ian M. Bird
Catherine M. Herzog
Matthew J. Ferrari
Indira Poojary
Robab Katani
Scott E. Lindner
Allen M. Minns
Randall Rossi
Paul A. Christensen
Brian Castillo
Jian Chen
Todd N. Eagar
Xin Yi
Picheng Zhao
Christopher Leveque
Randall J. Olsen
David W. Bernard
Jimmy Gollihar
Suresh V. Kuchipudi
James M. Musser
Vivek Kapur
author_sort Abhinay Gontu
title Limited window for donation of convalescent plasma with high live-virus neutralizing antibody titers for COVID-19 immunotherapy
title_short Limited window for donation of convalescent plasma with high live-virus neutralizing antibody titers for COVID-19 immunotherapy
title_full Limited window for donation of convalescent plasma with high live-virus neutralizing antibody titers for COVID-19 immunotherapy
title_fullStr Limited window for donation of convalescent plasma with high live-virus neutralizing antibody titers for COVID-19 immunotherapy
title_full_unstemmed Limited window for donation of convalescent plasma with high live-virus neutralizing antibody titers for COVID-19 immunotherapy
title_sort limited window for donation of convalescent plasma with high live-virus neutralizing antibody titers for covid-19 immunotherapy
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/29e9d16320ed452bba1c23cd05a61b50
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