SARS-CoV-2 Spike Protein S1-Mediated Endothelial Injury and Pro-Inflammatory State Is Amplified by Dihydrotestosterone and Prevented by Mineralocorticoid Antagonism
Men are disproportionately affected by the coronavirus disease-2019 (COVID-19), and face higher odds of severe illness and death compared to women. The vascular effects of androgen signaling and inflammatory cytokines in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-mediated endotheli...
Guardado en:
Autores principales: | Nitin Kumar, Yu Zuo, Srilakshmi Yalavarthi, Kristina L. Hunker, Jason S. Knight, Yogendra Kanthi, Andrea T. Obi, Santhi K. Ganesh |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/29ea2c7fc975437b97d2aac79e1dc36f |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Single, Double and Triple Blockade of RAAS in Alport Syndrome: Different Tools to Freeze the Evolution of the Disease
por: Antonio Mastrangelo, et al.
Publicado: (2021) -
Aplicaciones y proyecciones de los antagonistas del receptor de mineralocorticoides en el tratamiento de patologías cardiovasculares
por: Verdugo,Fernando J, et al.
Publicado: (2014) -
Systematic Review and Meta-Analysis of the Effect of Statins on Circulating E-Selectin, L-Selectin, and P-Selectin
por: Angelo Zinellu, et al.
Publicado: (2021) -
Improved Histoarchitectural Changes with Angiotensin Receptor Blockers in Early Testicular and Cauda Toxicity in Rats
por: Faddladdeen,Khadija Abduljalil, et al.
Publicado: (2019) -
2019 novel-coronavirus: Cardiovascular insights about risk factors, myocardial injury, therapy and clinical implications
por: Luigi Cappannoli, et al.
Publicado: (2020)