4-oxo-N-(4-hydroxyphenyl)retinamide: two independent ways to kill cancer cells.

4-oxo-N-(4-hydroxyphenyl)retinamide: two independent ways to kill cancer cells.

<h4>Background</h4>The retinoid 4-oxo-N-(4-hydroxyphenyl)retinamide (4-oxo-4-HPR) is a polar metabolite of fenretinide (4-HPR) very effective in killing cancer cells of different histotypes, able to inhibit 4-HPR-resistant cell growth and to act synergistically in combination with the pa...

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Autores principales: Paola Tiberio, Elena Cavadini, Gabriella Abolafio, Franca Formelli, Valentina Appierto
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/29f2061d33aa4882abbe95291e36ac2a
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