Targeted NGF siRNA delivery attenuates sympathetic nerve sprouting and deteriorates cardiac dysfunction in rats with myocardial infarction.
Nerve growth factor (NGF) is involved in nerve sprouting, hyper-innervation, angiogenesis, anti-apoptosis, and preservation of cardiac function after myocardial infarction (MI). Positively modulating NGF expression may represent a novel pharmacological strategy to improve post-infarction prognosis....
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Auteurs principaux: | Hesheng Hu, Yongli Xuan, Ye Wang, Mei Xue, Fei Suo, Xiaolu Li, Wenjuan Cheng, Xinran Li, Jie Yin, Ju Liu, Suhua Yan |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2014
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Sujets: | |
Accès en ligne: | https://doaj.org/article/29f46f7a47d94defabd9afd4e3e872c0 |
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