Staufen2-mediated RNA recognition and localization requires combinatorial action of multiple domains

The Staufen family of RNA-binding proteins are conserved microtubule dependent mRNA transporter factors. Here the authors use biochemical and functional approaches to characterize the RNA-binding properties of mouse Staufen 2 and study the mRNA binding capacity of its two domains dsRBDs 1 and 2.

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Autores principales:	Simone Heber, Imre Gáspár, Jan-Niklas Tants, Johannes Günther, Sandra M. Fernandez Moya, Robert Janowski, Anne Ephrussi, Michael Sattler, Dierk Niessing
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/29fa2d6445dc46718928f19f8f73daa7
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spelling	oai:doaj.org-article:29fa2d6445dc46718928f19f8f73daa72021-12-02T17:31:22ZStaufen2-mediated RNA recognition and localization requires combinatorial action of multiple domains10.1038/s41467-019-09655-32041-1723https://doaj.org/article/29fa2d6445dc46718928f19f8f73daa72019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09655-3https://doaj.org/toc/2041-1723The Staufen family of RNA-binding proteins are conserved microtubule dependent mRNA transporter factors. Here the authors use biochemical and functional approaches to characterize the RNA-binding properties of mouse Staufen 2 and study the mRNA binding capacity of its two domains dsRBDs 1 and 2.Simone HeberImre GáspárJan-Niklas TantsJohannes GüntherSandra M. Fernandez MoyaRobert JanowskiAnne EphrussiMichael SattlerDierk NiessingNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Simone Heber Imre Gáspár Jan-Niklas Tants Johannes Günther Sandra M. Fernandez Moya Robert Janowski Anne Ephrussi Michael Sattler Dierk Niessing Staufen2-mediated RNA recognition and localization requires combinatorial action of multiple domains
description	The Staufen family of RNA-binding proteins are conserved microtubule dependent mRNA transporter factors. Here the authors use biochemical and functional approaches to characterize the RNA-binding properties of mouse Staufen 2 and study the mRNA binding capacity of its two domains dsRBDs 1 and 2.
format	article
author	Simone Heber Imre Gáspár Jan-Niklas Tants Johannes Günther Sandra M. Fernandez Moya Robert Janowski Anne Ephrussi Michael Sattler Dierk Niessing
author_facet	Simone Heber Imre Gáspár Jan-Niklas Tants Johannes Günther Sandra M. Fernandez Moya Robert Janowski Anne Ephrussi Michael Sattler Dierk Niessing
author_sort	Simone Heber
title	Staufen2-mediated RNA recognition and localization requires combinatorial action of multiple domains
title_short	Staufen2-mediated RNA recognition and localization requires combinatorial action of multiple domains
title_full	Staufen2-mediated RNA recognition and localization requires combinatorial action of multiple domains
title_fullStr	Staufen2-mediated RNA recognition and localization requires combinatorial action of multiple domains
title_full_unstemmed	Staufen2-mediated RNA recognition and localization requires combinatorial action of multiple domains
title_sort	staufen2-mediated rna recognition and localization requires combinatorial action of multiple domains
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/29fa2d6445dc46718928f19f8f73daa7
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_version_	1718380602789462016

Staufen2-mediated RNA recognition and localization requires combinatorial action of multiple domains

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