Staufen2-mediated RNA recognition and localization requires combinatorial action of multiple domains

The Staufen family of RNA-binding proteins are conserved microtubule dependent mRNA transporter factors. Here the authors use biochemical and functional approaches to characterize the RNA-binding properties of mouse Staufen 2 and study the mRNA binding capacity of its two domains dsRBDs 1 and 2.

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Autores principales: Simone Heber, Imre Gáspár, Jan-Niklas Tants, Johannes Günther, Sandra M. Fernandez Moya, Robert Janowski, Anne Ephrussi, Michael Sattler, Dierk Niessing
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/29fa2d6445dc46718928f19f8f73daa7
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