Characterization and Prediction of the Non-Bonded Molecular Interactions between Racemic Ibuprofen and α-Lactose Monohydrate Crystals Produced from Melt Granulation and Slow Evaporation Crystallization
Granulation of racemic ibuprofen (±IBP) and α-lactose monohydrate (ALM) at a slightly lower (±IBP) melting point is an efficient method of binding the active pharmaceutical ingredients (API) and excipient in a binderless condition. However, the co-crystals may be formed from recrystallization of ±IB...
Guardado en:
Autores principales: | Zulfahmi Lukman, Nornizar Anuar, Noor Fitrah Abu Bakar, Norazah Abdul Rahman |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Department of Chemistry, Universitas Gadjah Mada
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/2a02a026738b44d480000ec634e1320c |
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