Characterization and Prediction of the Non-Bonded Molecular Interactions between Racemic Ibuprofen and α-Lactose Monohydrate Crystals Produced from Melt Granulation and Slow Evaporation Crystallization
Granulation of racemic ibuprofen (±IBP) and α-lactose monohydrate (ALM) at a slightly lower (±IBP) melting point is an efficient method of binding the active pharmaceutical ingredients (API) and excipient in a binderless condition. However, the co-crystals may be formed from recrystallization of ±IB...
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Format: | article |
Langue: | EN |
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Department of Chemistry, Universitas Gadjah Mada
2020
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Accès en ligne: | https://doaj.org/article/2a02a026738b44d480000ec634e1320c |
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