PoreDesigner for tuning solute selectivity in a robust and highly permeable outer membrane pore

Monodisperse angstrom-sized membrane proteins, found in biological membranes, are difficult to implement in synthetic industrial membranes. Here authors present a pore design procedure, to redesign the robust beta-barrel Outer Membrane Protein F (OmpF) with specific solute selectivity.

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Autores principales: Ratul Chowdhury, Tingwei Ren, Manish Shankla, Karl Decker, Matthew Grisewood, Jeevan Prabhakar, Carol Baker, John H. Golbeck, Aleksei Aksimentiev, Manish Kumar, Costas D. Maranas
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/2a0c785b9bbd49e8b546ce1e51fee59b
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spelling oai:doaj.org-article:2a0c785b9bbd49e8b546ce1e51fee59b2021-12-02T15:34:20ZPoreDesigner for tuning solute selectivity in a robust and highly permeable outer membrane pore10.1038/s41467-018-06097-12041-1723https://doaj.org/article/2a0c785b9bbd49e8b546ce1e51fee59b2018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06097-1https://doaj.org/toc/2041-1723Monodisperse angstrom-sized membrane proteins, found in biological membranes, are difficult to implement in synthetic industrial membranes. Here authors present a pore design procedure, to redesign the robust beta-barrel Outer Membrane Protein F (OmpF) with specific solute selectivity.Ratul ChowdhuryTingwei RenManish ShanklaKarl DeckerMatthew GrisewoodJeevan PrabhakarCarol BakerJohn H. GolbeckAleksei AksimentievManish KumarCostas D. MaranasNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ratul Chowdhury
Tingwei Ren
Manish Shankla
Karl Decker
Matthew Grisewood
Jeevan Prabhakar
Carol Baker
John H. Golbeck
Aleksei Aksimentiev
Manish Kumar
Costas D. Maranas
PoreDesigner for tuning solute selectivity in a robust and highly permeable outer membrane pore
description Monodisperse angstrom-sized membrane proteins, found in biological membranes, are difficult to implement in synthetic industrial membranes. Here authors present a pore design procedure, to redesign the robust beta-barrel Outer Membrane Protein F (OmpF) with specific solute selectivity.
format article
author Ratul Chowdhury
Tingwei Ren
Manish Shankla
Karl Decker
Matthew Grisewood
Jeevan Prabhakar
Carol Baker
John H. Golbeck
Aleksei Aksimentiev
Manish Kumar
Costas D. Maranas
author_facet Ratul Chowdhury
Tingwei Ren
Manish Shankla
Karl Decker
Matthew Grisewood
Jeevan Prabhakar
Carol Baker
John H. Golbeck
Aleksei Aksimentiev
Manish Kumar
Costas D. Maranas
author_sort Ratul Chowdhury
title PoreDesigner for tuning solute selectivity in a robust and highly permeable outer membrane pore
title_short PoreDesigner for tuning solute selectivity in a robust and highly permeable outer membrane pore
title_full PoreDesigner for tuning solute selectivity in a robust and highly permeable outer membrane pore
title_fullStr PoreDesigner for tuning solute selectivity in a robust and highly permeable outer membrane pore
title_full_unstemmed PoreDesigner for tuning solute selectivity in a robust and highly permeable outer membrane pore
title_sort poredesigner for tuning solute selectivity in a robust and highly permeable outer membrane pore
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/2a0c785b9bbd49e8b546ce1e51fee59b
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