Sequences flanking the core-binding site modulate glucocorticoid receptor structure and activity

Sequences flanking the core-binding site modulate glucocorticoid receptor structure and activity

To modulate gene expression, the glucocorticoid receptor binds to response elements (RE) that vary in sequence. Here, the authors show that RE sequences can modulate glucocorticoid receptor structure and activity, which might provide regulatory specificity towards individual target genes.

Guardado en:
Detalles Bibliográficos
Autores principales: Stefanie Schöne, Marcel Jurk, Mahdi Bagherpoor Helabad, Iris Dror, Isabelle Lebars, Bruno Kieffer, Petra Imhof, Remo Rohs, Martin Vingron, Morgane Thomas-Chollier, Sebastiaan H. Meijsing
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/2a1ad04ab2d040d4bcff1e24f2469042
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Internet

https://doaj.org/article/2a1ad04ab2d040d4bcff1e24f2469042

Ejemplares similares