Miniature neurotransmission is required to maintain Drosophila synaptic structures during ageing

Synaptic structures disintegrate and fragment as ageing progresses. Here the authors find that miniature neurotransmission is required to maintain adult motor synapse structures in Drosophila and that increasing miniature events can preserve motor ability during ageing.

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Autores principales: Soumya Banerjee, Samuel Vernon, Wei Jiao, Ben Jiwon Choi, Evelyne Ruchti, Jamshid Asadzadeh, Olivier Burri, R. Steven Stowers, Brian D. McCabe
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/2a1bfcff0afc45c6aaef4d99afe32773
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Sumario:Synaptic structures disintegrate and fragment as ageing progresses. Here the authors find that miniature neurotransmission is required to maintain adult motor synapse structures in Drosophila and that increasing miniature events can preserve motor ability during ageing.