All-trans-retinoic acid activates the pro-invasive Src-YAP-Interleukin 6 axis in triple-negative MDA-MB-231 breast cancer cells while cerivastatin reverses this action

Abstract All-trans-retinoic acid (RA), the active metabolite of vitamin A, can reduce the malignant phenotype in some types of cancer and paradoxically also can promote cancer growth and invasion in others. For instance, it has been reported that RA induces tumor suppression in tumor xenografts of M...

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Auteurs principaux: Belén Mezquita, Pau Mezquita, Montserrat Pau, Laura Gasa, Lourdes Navarro, Mireia Samitier, Miquel Pons, Cristóbal Mezquita
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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R
Q
Accès en ligne:https://doaj.org/article/2a1dc9fb90a2496e9e3925c46c9cd114
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