A pre-formulation study of tetracaine loaded in optimized nanostructured lipid carriers

A pre-formulation study of tetracaine loaded in optimized nanostructured lipid carriers

Abstract Tetracaine (TTC) is a local anesthetic broadly used for topical and spinal blockade, despite its systemic toxicity. Encapsulation in nanostructured lipid carriers (NLC) may prolong TTC delivery at the site of injection, reducing such toxicity. This work reports the development of NLC loadin...

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Autores principales: Simone R. Castro, Lígia N. M. Ribeiro, Márcia C. Breitkreitz, Viviane A. Guilherme, Gustavo H. Rodrigues da Silva, Hery Mitsutake, Ana C. S. Alcântara, Fabiano Yokaichiya, Margareth K. K. D. Franco, Daniel Clemens, Ben Kent, Marcelo Lancellotti, Daniele R. de Araújo, Eneida de Paula
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/2a392a9650a24606a11c70d5ae2df5f8
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