A pre-formulation study of tetracaine loaded in optimized nanostructured lipid carriers

Abstract Tetracaine (TTC) is a local anesthetic broadly used for topical and spinal blockade, despite its systemic toxicity. Encapsulation in nanostructured lipid carriers (NLC) may prolong TTC delivery at the site of injection, reducing such toxicity. This work reports the development of NLC loadin...

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Auteurs principaux:	Simone R. Castro, Lígia N. M. Ribeiro, Márcia C. Breitkreitz, Viviane A. Guilherme, Gustavo H. Rodrigues da Silva, Hery Mitsutake, Ana C. S. Alcântara, Fabiano Yokaichiya, Margareth K. K. D. Franco, Daniel Clemens, Ben Kent, Marcelo Lancellotti, Daniele R. de Araújo, Eneida de Paula
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2021
Sujets:	Medicine R Science Q
Accès en ligne:	https://doaj.org/article/2a392a9650a24606a11c70d5ae2df5f8
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A pre-formulation study of tetracaine loaded in optimized nanostructured lipid carriers

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