A randomized controlled trial on the effects induced by robot-assisted and usual-care rehabilitation on upper limb muscle synergies in post-stroke subjects

Abstract Muscle synergies are hypothesized to reflect connections among motoneurons in the spinal cord activated by central commands and sensory feedback. Robotic rehabilitation of upper limb in post-stroke subjects has shown promising results in terms of improvement of arm function and motor contro...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	T. Lencioni, L. Fornia, T. Bowman, A. Marzegan, A. Caronni, A. Turolla, J. Jonsdottir, I. Carpinella, M. Ferrarin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/2a39871814a7483685c68cae30907ad8
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:2a39871814a7483685c68cae30907ad8
record_format	dspace
spelling	oai:doaj.org-article:2a39871814a7483685c68cae30907ad82021-12-02T13:34:31ZA randomized controlled trial on the effects induced by robot-assisted and usual-care rehabilitation on upper limb muscle synergies in post-stroke subjects10.1038/s41598-021-84536-82045-2322https://doaj.org/article/2a39871814a7483685c68cae30907ad82021-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-84536-8https://doaj.org/toc/2045-2322Abstract Muscle synergies are hypothesized to reflect connections among motoneurons in the spinal cord activated by central commands and sensory feedback. Robotic rehabilitation of upper limb in post-stroke subjects has shown promising results in terms of improvement of arm function and motor control achieved by reassembling muscle synergies into a set more similar to that of healthy people. However, in stroke survivors the potentially neurophysiological changes induced by robot-mediated learning versus usual care have not yet been investigated. We quantified upper limb motor deficits and the changes induced by rehabilitation in 32 post-stroke subjects through the movement analysis of two virtual untrained tasks of object placing and pronation. The sample analyzed in this study is part of a larger bi-center study and included all subjects who underwent kinematic analysis and were randomized into robot and usual care groups. Post-stroke subjects who followed robotic rehabilitation showed larger improvements in axial-to-proximal muscle synergies with respect to those who underwent usual care. This was associated to a significant improvement of the proximal kinematics. Both treatments had negative effects in muscle synergies controlling the distal district. This study supports the definition of new rehabilitative treatments for improving the neurophysiological recovery after stroke.T. LencioniL. ForniaT. BowmanA. MarzeganA. CaronniA. TurollaJ. JonsdottirI. CarpinellaM. FerrarinNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q T. Lencioni L. Fornia T. Bowman A. Marzegan A. Caronni A. Turolla J. Jonsdottir I. Carpinella M. Ferrarin A randomized controlled trial on the effects induced by robot-assisted and usual-care rehabilitation on upper limb muscle synergies in post-stroke subjects
description	Abstract Muscle synergies are hypothesized to reflect connections among motoneurons in the spinal cord activated by central commands and sensory feedback. Robotic rehabilitation of upper limb in post-stroke subjects has shown promising results in terms of improvement of arm function and motor control achieved by reassembling muscle synergies into a set more similar to that of healthy people. However, in stroke survivors the potentially neurophysiological changes induced by robot-mediated learning versus usual care have not yet been investigated. We quantified upper limb motor deficits and the changes induced by rehabilitation in 32 post-stroke subjects through the movement analysis of two virtual untrained tasks of object placing and pronation. The sample analyzed in this study is part of a larger bi-center study and included all subjects who underwent kinematic analysis and were randomized into robot and usual care groups. Post-stroke subjects who followed robotic rehabilitation showed larger improvements in axial-to-proximal muscle synergies with respect to those who underwent usual care. This was associated to a significant improvement of the proximal kinematics. Both treatments had negative effects in muscle synergies controlling the distal district. This study supports the definition of new rehabilitative treatments for improving the neurophysiological recovery after stroke.
format	article
author	T. Lencioni L. Fornia T. Bowman A. Marzegan A. Caronni A. Turolla J. Jonsdottir I. Carpinella M. Ferrarin
author_facet	T. Lencioni L. Fornia T. Bowman A. Marzegan A. Caronni A. Turolla J. Jonsdottir I. Carpinella M. Ferrarin
author_sort	T. Lencioni
title	A randomized controlled trial on the effects induced by robot-assisted and usual-care rehabilitation on upper limb muscle synergies in post-stroke subjects
title_short	A randomized controlled trial on the effects induced by robot-assisted and usual-care rehabilitation on upper limb muscle synergies in post-stroke subjects
title_full	A randomized controlled trial on the effects induced by robot-assisted and usual-care rehabilitation on upper limb muscle synergies in post-stroke subjects
title_fullStr	A randomized controlled trial on the effects induced by robot-assisted and usual-care rehabilitation on upper limb muscle synergies in post-stroke subjects
title_full_unstemmed	A randomized controlled trial on the effects induced by robot-assisted and usual-care rehabilitation on upper limb muscle synergies in post-stroke subjects
title_sort	randomized controlled trial on the effects induced by robot-assisted and usual-care rehabilitation on upper limb muscle synergies in post-stroke subjects
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/2a39871814a7483685c68cae30907ad8
work_keys_str_mv	AT tlencioni arandomizedcontrolledtrialontheeffectsinducedbyrobotassistedandusualcarerehabilitationonupperlimbmusclesynergiesinpoststrokesubjects AT lfornia arandomizedcontrolledtrialontheeffectsinducedbyrobotassistedandusualcarerehabilitationonupperlimbmusclesynergiesinpoststrokesubjects AT tbowman arandomizedcontrolledtrialontheeffectsinducedbyrobotassistedandusualcarerehabilitationonupperlimbmusclesynergiesinpoststrokesubjects AT amarzegan arandomizedcontrolledtrialontheeffectsinducedbyrobotassistedandusualcarerehabilitationonupperlimbmusclesynergiesinpoststrokesubjects AT acaronni arandomizedcontrolledtrialontheeffectsinducedbyrobotassistedandusualcarerehabilitationonupperlimbmusclesynergiesinpoststrokesubjects AT aturolla arandomizedcontrolledtrialontheeffectsinducedbyrobotassistedandusualcarerehabilitationonupperlimbmusclesynergiesinpoststrokesubjects AT jjonsdottir arandomizedcontrolledtrialontheeffectsinducedbyrobotassistedandusualcarerehabilitationonupperlimbmusclesynergiesinpoststrokesubjects AT icarpinella arandomizedcontrolledtrialontheeffectsinducedbyrobotassistedandusualcarerehabilitationonupperlimbmusclesynergiesinpoststrokesubjects AT mferrarin arandomizedcontrolledtrialontheeffectsinducedbyrobotassistedandusualcarerehabilitationonupperlimbmusclesynergiesinpoststrokesubjects AT tlencioni randomizedcontrolledtrialontheeffectsinducedbyrobotassistedandusualcarerehabilitationonupperlimbmusclesynergiesinpoststrokesubjects AT lfornia randomizedcontrolledtrialontheeffectsinducedbyrobotassistedandusualcarerehabilitationonupperlimbmusclesynergiesinpoststrokesubjects AT tbowman randomizedcontrolledtrialontheeffectsinducedbyrobotassistedandusualcarerehabilitationonupperlimbmusclesynergiesinpoststrokesubjects AT amarzegan randomizedcontrolledtrialontheeffectsinducedbyrobotassistedandusualcarerehabilitationonupperlimbmusclesynergiesinpoststrokesubjects AT acaronni randomizedcontrolledtrialontheeffectsinducedbyrobotassistedandusualcarerehabilitationonupperlimbmusclesynergiesinpoststrokesubjects AT aturolla randomizedcontrolledtrialontheeffectsinducedbyrobotassistedandusualcarerehabilitationonupperlimbmusclesynergiesinpoststrokesubjects AT jjonsdottir randomizedcontrolledtrialontheeffectsinducedbyrobotassistedandusualcarerehabilitationonupperlimbmusclesynergiesinpoststrokesubjects AT icarpinella randomizedcontrolledtrialontheeffectsinducedbyrobotassistedandusualcarerehabilitationonupperlimbmusclesynergiesinpoststrokesubjects AT mferrarin randomizedcontrolledtrialontheeffectsinducedbyrobotassistedandusualcarerehabilitationonupperlimbmusclesynergiesinpoststrokesubjects
_version_	1718392784635822080

A randomized controlled trial on the effects induced by robot-assisted and usual-care rehabilitation on upper limb muscle synergies in post-stroke subjects

Ejemplares similares