Crystal structures of U6 snRNA-specific terminal uridylyltransferase

After transcription the 3′-end of U6 snRNA is oligo-uridylylated by the terminal uridylyltransferase TUT1. Here the authors present the crystal structure of human TUT1 and give insights into the mechanism of 3′-end uridylylation by the enzyme.

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Autores principales:	Seisuke Yamashita, Yuko Takagi, Takashi Nagaike, Kozo Tomita
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2a46149eda164db9ab1f82348eeccc5c
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spelling	oai:doaj.org-article:2a46149eda164db9ab1f82348eeccc5c2021-12-02T14:41:10ZCrystal structures of U6 snRNA-specific terminal uridylyltransferase10.1038/ncomms157882041-1723https://doaj.org/article/2a46149eda164db9ab1f82348eeccc5c2017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15788https://doaj.org/toc/2041-1723After transcription the 3′-end of U6 snRNA is oligo-uridylylated by the terminal uridylyltransferase TUT1. Here the authors present the crystal structure of human TUT1 and give insights into the mechanism of 3′-end uridylylation by the enzyme.Seisuke YamashitaYuko TakagiTakashi NagaikeKozo TomitaNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Seisuke Yamashita Yuko Takagi Takashi Nagaike Kozo Tomita Crystal structures of U6 snRNA-specific terminal uridylyltransferase
description	After transcription the 3′-end of U6 snRNA is oligo-uridylylated by the terminal uridylyltransferase TUT1. Here the authors present the crystal structure of human TUT1 and give insights into the mechanism of 3′-end uridylylation by the enzyme.
format	article
author	Seisuke Yamashita Yuko Takagi Takashi Nagaike Kozo Tomita
author_facet	Seisuke Yamashita Yuko Takagi Takashi Nagaike Kozo Tomita
author_sort	Seisuke Yamashita
title	Crystal structures of U6 snRNA-specific terminal uridylyltransferase
title_short	Crystal structures of U6 snRNA-specific terminal uridylyltransferase
title_full	Crystal structures of U6 snRNA-specific terminal uridylyltransferase
title_fullStr	Crystal structures of U6 snRNA-specific terminal uridylyltransferase
title_full_unstemmed	Crystal structures of U6 snRNA-specific terminal uridylyltransferase
title_sort	crystal structures of u6 snrna-specific terminal uridylyltransferase
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/2a46149eda164db9ab1f82348eeccc5c
work_keys_str_mv	AT seisukeyamashita crystalstructuresofu6snrnaspecificterminaluridylyltransferase AT yukotakagi crystalstructuresofu6snrnaspecificterminaluridylyltransferase AT takashinagaike crystalstructuresofu6snrnaspecificterminaluridylyltransferase AT kozotomita crystalstructuresofu6snrnaspecificterminaluridylyltransferase
_version_	1718389980568485888

Crystal structures of U6 snRNA-specific terminal uridylyltransferase

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