Autozygosity influences cardiometabolic disease-associated traits in the AWI-Gen sub-Saharan African study

The prevalence of cardiometabolic diseases (CMDs) is increasing rapidly across Africa. Here, the authors investigate autozygosity in CMD-associated traits in over 10,000 sub-Saharan African individuals, showing these traits are influenced by sex-specific inbreeding depression and environmental inter...

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Autores principales:	Francisco C. Ceballos, Scott Hazelhurst, David W. Clark, Godfred Agongo, Gershim Asiki, Palwende R. Boua, F. Xavier Gómez-Olivé, Felistas Mashinya, Shane Norris, James F. Wilson, Michèle Ramsay
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2a623d056cd2423c8fc5148894109e63
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spelling	oai:doaj.org-article:2a623d056cd2423c8fc5148894109e632021-12-02T17:31:10ZAutozygosity influences cardiometabolic disease-associated traits in the AWI-Gen sub-Saharan African study10.1038/s41467-020-19595-y2041-1723https://doaj.org/article/2a623d056cd2423c8fc5148894109e632020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19595-yhttps://doaj.org/toc/2041-1723The prevalence of cardiometabolic diseases (CMDs) is increasing rapidly across Africa. Here, the authors investigate autozygosity in CMD-associated traits in over 10,000 sub-Saharan African individuals, showing these traits are influenced by sex-specific inbreeding depression and environmental interactions.Francisco C. CeballosScott HazelhurstDavid W. ClarkGodfred AgongoGershim AsikiPalwende R. BouaF. Xavier Gómez-OlivéFelistas MashinyaShane NorrisJames F. WilsonMichèle RamsayNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Francisco C. Ceballos Scott Hazelhurst David W. Clark Godfred Agongo Gershim Asiki Palwende R. Boua F. Xavier Gómez-Olivé Felistas Mashinya Shane Norris James F. Wilson Michèle Ramsay Autozygosity influences cardiometabolic disease-associated traits in the AWI-Gen sub-Saharan African study
description	The prevalence of cardiometabolic diseases (CMDs) is increasing rapidly across Africa. Here, the authors investigate autozygosity in CMD-associated traits in over 10,000 sub-Saharan African individuals, showing these traits are influenced by sex-specific inbreeding depression and environmental interactions.
format	article
author	Francisco C. Ceballos Scott Hazelhurst David W. Clark Godfred Agongo Gershim Asiki Palwende R. Boua F. Xavier Gómez-Olivé Felistas Mashinya Shane Norris James F. Wilson Michèle Ramsay
author_facet	Francisco C. Ceballos Scott Hazelhurst David W. Clark Godfred Agongo Gershim Asiki Palwende R. Boua F. Xavier Gómez-Olivé Felistas Mashinya Shane Norris James F. Wilson Michèle Ramsay
author_sort	Francisco C. Ceballos
title	Autozygosity influences cardiometabolic disease-associated traits in the AWI-Gen sub-Saharan African study
title_short	Autozygosity influences cardiometabolic disease-associated traits in the AWI-Gen sub-Saharan African study
title_full	Autozygosity influences cardiometabolic disease-associated traits in the AWI-Gen sub-Saharan African study
title_fullStr	Autozygosity influences cardiometabolic disease-associated traits in the AWI-Gen sub-Saharan African study
title_full_unstemmed	Autozygosity influences cardiometabolic disease-associated traits in the AWI-Gen sub-Saharan African study
title_sort	autozygosity influences cardiometabolic disease-associated traits in the awi-gen sub-saharan african study
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/2a623d056cd2423c8fc5148894109e63
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Autozygosity influences cardiometabolic disease-associated traits in the AWI-Gen sub-Saharan African study

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