Structure-based machine-guided mapping of amyloid sequence space reveals uncharted sequence clusters with higher solubilities
An increasing number of amyloid structures are determined. Here, the authors present the structure-based amyloid core sequence prediction method Cordax that is based on machine learning and allows the detection of aggregation-prone regions with higher solubility, disorder and surface exposure, and f...
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| Main Authors: | , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2020
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| Subjects: | |
| Online Access: | https://doaj.org/article/2a64a32adfa14ef9a2a2d237d6f0b10b |
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